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· · COA & SDS すべての製品に適用 · 在庫品は当日出荷 ホーム 目標/経路/疾患別 シグナル伝達経路によって TGF-β/Smad プロテインキナーゼC Darovasertib - Moligand™, ≥99% , Inhibitor of protein kinase C alpha;Inhibitor of protein kinase C theta, CAS No.1874276-76-2, Inhibitor of protein kinase C alpha;Inhibitor of protein kinase C theta Darovasertib - Moligand™, ≥99% , Inhibitor of protein kinase C alpha;Inhibitor of protein kinase C theta, CAS No.1874276-76-2, Inhibitor of protein kinase C alpha;Inhibitor of protein kinase C theta
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99% Synonyms
UNII-E0YF0M8O09 | EN300-26212118 | darovasertib | TOLTERODINE [WHO-DD] | 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl]-6-[3-(trifluoromethyl)pyridin-2-yl]pyrazine-2-carboxamide | AKOS040758778 | GTPL11186 | NSC800030 | NSC-800030 | US9452998,
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
概要 Information
Darovasertib (LXS-196) Darovasertib (LXS-196, IDE-196) is a selective inhibitor of protein kinase C (PKC) .
Targets
PKC
Specifications 同義語
UNII-E0YF0M8O09 | EN300-26212118 | darovasertib | TOLTERODINE [WHO-DD] | 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl]-6-[3-(trifluoromethyl)pyridin-2-yl]pyrazine-2-carboxamide | AKOS040758778 | GTPL11186 | NSC800030 | NSC-800030 | US9452998,
生化学的・生理学的メカニズム
Darovasertib (LXS-196, IDE-196) is a selective inhibitor of protein kinase C (PKC).
入荷
Ice chest + Ice pads
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
作用メカニズム
Inhibitor of protein kinase C alpha;Inhibitor of protein kinase C theta
製品の性質 ALogP 1.6 hba_count 5 HBD数 3 回転可能な結合 5
名前と識別子 パブケム・シド 504772893 パブケム・シド・ウル https://pubchem.ncbi.nlm.nih.gov/substance/504772893 カノニカル・スマイル CC1(CCN(CC1)C2=C(N=CC=C2)NC(=O)C3=NC(=CN=C3N)C4=C(C=CC=N4)C(F)(F)F)N IUPAC Name 3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl]-6-[3-(trifluoromethyl)pyridin-2-yl]pyrazine-2-carboxamide InChIKey XXJXHXJWQSCNPX-UHFFFAOYSA-N INCHI 1S/C22H23F3N8O/c1-21(27)6-10-33(11-7-21)15-5-3-9-29-19(15)32-20(34)17-18(26)30-12-14(31-17)16-13(22(23,24)25)4-2-8-28-16/h2-5,8-9,12H,6-7,10-11,27H2,1H3,(H2,26,30)(H,29,32,34) 異性体SMILES CC1(CCN(CC1)C2=C(N=CC=C2)NC(=O)C3=NC(=CN=C3N)C4=C(C=CC=N4)C(F)(F)F)N 分子量 472.47 Reaxy-Rn 29306963 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29306963&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds 分類 Diazines Subclass Pyrazines Intermediate Tree Nodes Pyrazine carboxylic acids and derivatives Direct Parent Pyrazinecarboxamides Alternative Parents Dialkylarylamines 2-heteroaryl carboxamides Aminopyridines and derivatives Aminopyrazines Aminopiperidines Imidolactams Vinylogous amides Heteroaromatic compounds Secondary carboxylic acid amides Amino acids and derivatives Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organofluorides Organic oxides Monoalkylamines Hydrocarbon derivatives Alkyl fluorides Molecular Framework Aromatic heteromonocyclic compounds Substituents Pyrazinecarboxamide - 2-heteroaryl carboxamide - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Aminopyridine - Aminopyrazine - 4-aminopiperidine - Imidolactam - Pyridine - Piperidine - Heteroaromatic compound - Vinylogous amide - Tertiary amine - Secondary carboxylic acid amide - Carboxamide group - Amino acid or derivatives - Azacycle - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Primary amine - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Primary aliphatic amine - Amine - Alkyl halide - Alkyl fluoride - Aromatic heteromonocyclic compound 説明 This compound belongs to the class of organic compounds known as pyrazinecarboxamides. These are compounds containing a pyrazine ring which bears a carboxamide. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3 D構造 関連ターゲット（人間） 関連ターゲット（非人間） 作用メカニズム 証明書（CoA、COO、BSE/TSEと分析図） 化学的性質と物理的性質 溶解度 Solubility (25°C) In vitro DMSO: 60 mg/mL (126.99 mM); Ethanol: 20 mg/mL (42.33 mM); Water: Insoluble; DMSO（mg / mL） 最大溶解度 22 DMSO（mM） 最大溶解度 46.5638029927826 水（mg / mL） 最大溶解度 ＜1 分子量 472.500 g/mol XLogP3 1.900 Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 11 Rotatable Bond Count 4 Exact Mass 472.195 Da Monoisotopic Mass 472.195 Da Topological Polar Surface Area 136.000 Ų Heavy Atom Count 34 Formal Charge 0 Complexity 702.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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