DCOIT - Moligand™, 10 mM in DMSO , CAS No.64359-81-5

CAS: 64359-81-5 Cat. No.: D1500728 分子式: C₁₁H₁₇Cl₂NOS 分子量: 282.22 EC番号: 264-843-8

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

DCOIT is a representative isothiazolinone that stimulates the gonadotropin-releasing hormone receptor ( GnRHR )-mediated synthesis of follicle-stimulating hormone and luteinizing hormone in the brain. DCOIT interferes with G protein-coupled receptors, MAPK and Ca 2+ signaling cascades.

Specifications

仕様と純度

Moligand™, 10 mM in DMSO

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

AGONIST

名前と識別子

• 異性体SMILES: CCCCCCCCN1C(=O)C(=C(S1)Cl)Cl
• RTECS: NX8157075
• 分子量: 282.22
• Reaxy-Rn: 1110842
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1110842&ln=

化学的性質と物理的性質

• 融点（°C）: 42 °C

参考文献

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2. Tongtong Ding, Luyao Xu, Xiangting Liu, Liang Ma, Yingxin Cui, Dalong Li, Xiuhua Sun, Changlu Gao.  (2022)  A Cu2O-based marine antifouling coating with controlled release of copper ion mediated by amphiphilic PLMA-b-PDMAEMA copolymers.  PROGRESS IN ORGANIC COATINGS,      [PMID:] [10.1016/j.porgcoat.2022.107003]

3. Abid Ali, Lina Song, Jiankun Hu, Jingxian Jiang, Qingqing Rao, Muhammad Shoaib, Shah Fahad, Yongjie Cai, Xiaoli Zhan, Fengqiu Chen, Qinghua Zhang.  (2020)  Synthesis and characterization of caprolactone based polyurethane with degradable and antifouling performance.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,      [PMID:] [10.1016/j.cjche.2020.11.007]

4. Qiao Sen, Cao Hongjie, Yang Yue, Jin Ruofei, Zhou Jiti.  (2020)  Preparation and antifouling performance of PVDF-DCOIT composite hollow fiber membranes.  KOREAN JOURNAL OF CHEMICAL ENGINEERING,  37  (3): (497-504).  [PMID:] [10.1007/s11814-019-0436-2]

5. Peng-Yu Zhu, Tian-Xiao Liang, Muhammad Arslan Hafeez, Muhammad Yasir, Dan-Qing Feng, Chun-Feng Ma, Cheng Zhang, Lin Liu.  (2024)  A novel strategy for design of mechanically robust antifouling coatings via bifunctional domain engineering.  Materials Today Chemistry,      [PMID:] [10.1016/j.mtchem.2024.102207]

6. Shuqing Wei, Guangling He, Yuhao Yue, Qianju Liu, Xinhao Liu, Liangmin Yu, Lei Dong.  (2025)  Construction and properties of hydrogel microlayer on the surface of water-based self-polishing antifouling resin coating.  PROGRESS IN ORGANIC COATINGS,      [PMID:] [10.1016/j.porgcoat.2025.109259]

7. Jiayin Li, Guangmeng Chen, Shuaipeng Wang, Jinyue Dai, Shuan Liu, Guangming Lu, Weiwei Zhao, Xiaoqing Liu.  (2025)  Sea-water degradable self-polishing epoxy thermosets for antifouling coatings.  PROGRESS IN ORGANIC COATINGS,      [PMID:] [10.1016/j.porgcoat.2025.109162]

8. Junqiao Zhou, Jiayin Li, Cong Cheng, YuJuan Yao, Yu Li, Hao Liu, Laiyan Wu.  (2024)  Unraveling the binding behavior of the antifouling biocide 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one with human serum albumin: Multi-spectroscopic, atomic force microscope, computational simulation, and esterase activity.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:38906347] [10.1016/j.ijbiomac.2024.133266]

9. Jiaxin Zhang, Libing Cai, Lin Wang, Lianhui Zhang, Nan Meng, Andong Chen, Qiao Ma.  (2026)  Marine antifouling biocide 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one disrupts sediment microbiome structure and function: insights from absolute quantification and enzyme activity dynamics.  APPLIED AND ENVIRONMENTAL MICROBIOLOGY,      [PMID:42496154] [10.1128/aem.00819-26]