DDR1-IN-5 - ≥99% , CAS No.2416022-90-5

CAS: 2416022-90-5 Cat. No.: D647022 分子式: C₂₂H₁₃F₃N₆O 分子量: 434.37

GRADE & PURITY ≥99%

Storage

Store at 2-8°C,Protected from light,Desiccated

Shipped In

Wet ice

概要

DDR1-IN-5 is a selective Discoidin Domain Receptor family, member 1 (DDR1) inhibitor with an IC 50 of 7.36 nM. DDR1-IN-5 inhibits auto-phosphorylation DDR1b (Y513) with an IC 50 of 4.1 nM. DDR1-IN-5 has anti-cancer activity

In Vitro

DDR1-IN-5 (compound 121; for 24 hours) inhibits collagen production in human hepatic stellate cell LX-2 (IC 50 =62 nM). DDR1-IN-5 (72 hours) has cytotoxicity in LX-2 cells (CC 50 >40 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:DDR1 7.36 nM (IC 50 )

Specifications

仕様と純度

≥99%

生化学的・生理学的メカニズム

DDR1-IN-5 is a selective Discoidin Domain Receptor family, member 1 (DDR1) inhibitor with an IC 50 of 7.36 nM. DDR1-IN-5 inhibits auto-phosphorylation DDR1b (Y513) with an IC 50 of 4.1 nM. DDR1-IN-5 has anti-cancer activity.

保管条件

Store at 2-8°C,Protected from light,Desiccated

入荷

Wet ice

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

INHIBITOR

純度

≥99%

名前と識別子

• 分子量: 434.37

化学的性質と物理的性質

• 溶解度: DMSO : 2.78 mg/mL (6.40 mM; ultrasonic and warming and heat to 60°C)