≥98% ベースライン干渉を最小限に抑える必要がある、感度の高いクロマトグラフィーおよび分析ワークフロー向け。
Store at -20°C Ice chest + Ice pads に出荷。正確な仕様については、ロット固有の COA をご確認ください。
SDS、COA、データシート、仕様書をダウンロードできます。ロット固有の COA はロット番号検索で入手可能です。
クロマトグラフィー、有機合成、クロスカップリング反応に関する 0 件の査読済み論文で引用されています。
Information
Demethyleneberberine (DMB), a component of Cortex Phellodendri Chinensis (CPC), significantly alleviates the weight loss and diminishesmyeloperoxidase (MPO)activity, while significantly reduces the production of pro-inflammatory cytokines, such asinterleukin (IL)-6andtumor necrosis factor-α (TNF-α), and inhibits the activation ofNF-κBsignaling pathway. Demethyleneberberine (DMB) potentially ameliorates NAFLD (Non-alcoholic fatty liver disease) by activating
Targets
NF-κB ; MPO ; IL-6 ; TNF-α ; IL-1β 33791,
危険性、取扱い、保管、および規制遵守を網羅した包括的な文書。
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| Kingdom | Organic compounds |
|---|---|
| Superclass | Alkaloids and derivatives |
| 分類 | Protoberberine alkaloids and derivatives |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Protoberberine alkaloids and derivatives |
| Alternative Parents | Isoquinolines and derivatives Anisoles Alkyl aryl ethers 1-hydroxy-2-unsubstituted benzenoids Pyridinium derivatives Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives Organic cations |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Protoberberine skeleton - Isoquinoline - Anisole - Alkyl aryl ether - 1-hydroxy-2-unsubstituted benzenoid - Benzenoid - Pyridinium - Pyridine - Heteroaromatic compound - Ether - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Organic cation - Aromatic heteropolycyclic compound |
| 説明 | This compound belongs to the class of organic compounds known as protoberberine alkaloids and derivatives. These are alkaloids with a structure based on a protoberberine moiety, which consists of a 5,6-dihydrodibenzene moiety fused to a quinolizinium and forming 5,6-Dihydrodibenzo(a,g)quinolizinium skeleton. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | 日付 | 商品 |
|---|---|---|---|
 H2220065 | Certificate of Analysis | Jun 09, 2025 | D412894 |
| H2220066 | Certificate of Analysis | Jun 09, 2025 | D412894 |
| H2220067 | Certificate of Analysis | Jun 09, 2025 | D412894 |
| H2220068 | Certificate of Analysis | Jun 09, 2025 | D412894 |
| H2220069 | Certificate of Analysis | Jun 09, 2025 | D412894 |
| 溶解度 | Solubility (25°C) In vitro DMSO: 3 mg/mL (9.24 mM); |
|---|---|
| 感度 | Light sensitive |
| 分子量 | 324.300 g/mol |
| XLogP3 | 3.100 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 2 |
| Exact Mass | 324.124 Da |
| Monoisotopic Mass | 324.124 Da |
| Topological Polar Surface Area | 62.800 Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 1 |
| Complexity | 447.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
