Diclofenac Potassium - 10mM in DMSO , Cyclooxygenase inhibitor, CAS No.15307-81-0, Cyclooxygenase inhibitor

CAS: 15307-81-0 Cat. No.: D409053 分子式: C₁₄H₁₀Cl₂KNO₂ 分子量: 334.24 EC番号: 630-422-6 PubChem CID: 23667642

GRADE & PURITY 10mM in DMSO

Synonyms

CGP-45840B | potassium 2-(2-(2,6-dichlorophenylamino)phenyl)acetate

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Information

Diclofenac potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
In vitro

The primary mechanism of diclofenac responsible for its anti-inflammatory, antipyretic, and analgesic action is thought to be inhibition of prostaglandin synthesis by inhibition of cyclooxygenase (COX). It also appears to exhibit bacteriostatic activity by inhibiting bacterial DNA synthesis. Inhibition of COX also decreases prostaglandins in the epithelium of the stomach, making it more sensitive to corrosion by gastric acid. This is also the main side effect of diclofenac. Diclofenac has a low to moderate preference to block the COX2-isoenzyme (approximately 10-fold) and is said to have, therefore, a somewhat lower incidence of gastrointestinal complaints than noted with indomethacin and aspirin.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

同義語

CGP-45840B | potassium 2-(2-(2,6-dichlorophenylamino)phenyl)acetate

仕様と純度

10mM in DMSO

生化学的・生理学的メカニズム

Diclofenac potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

INHIBITOR

作用メカニズム

Cyclooxygenase inhibitor

名前と識別子

異性体SMILES

C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=CC=C2Cl)Cl.[K+]

PubChem CID

23667642

分子量

334.24