Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 23 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Canonical Smiles | CCOC(=O)CC(=O)OCC |
|---|---|
| IUPAC Name | diethyl propanedioate |
| InChIKey | IYXGSMUGOJNHAZ-UHFFFAOYSA-N |
| INCHI | 1S/C7H12O4/c1-3-10-6(8)5-7(9)11-4-2/h3-5H2,1-2H3 |
| Isomeric SMILES | CCOC(=O)CC(=O)OCC |
| WGK Germany | 1 |
| RTECS | OO0700000 |
| Molecular Weight | 160.17 |
| Beilstein | 774687 |
| Reaxy-Rn | 774687 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=774687&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Carboxylic acids and derivatives |
| Subclass | Dicarboxylic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Dicarboxylic acids and derivatives |
| Alternative Parents | 1,3-dicarbonyl compounds Carboxylic acid esters Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | 1,3-dicarbonyl compound - Dicarboxylic acid or derivatives - Carboxylic acid ester - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups. |
| External Descriptors | Not available |
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Sensitivity | Moisture sensitive. |
|---|---|
| Refractive Index | 1.4143 |
| Flash Point(°F) | 194 °F |
| Flash Point(°C) | 93℃ |
| Boil Point(°C) | 198-199°C |
| Melt Point(°C) | -50°C |
| Molecular Weight | 160.170 g/mol |
| XLogP3 | 1.000 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 6 |
| Exact Mass | 160.074 Da |
| Monoisotopic Mass | 160.074 Da |
| Topological Polar Surface Area | 52.600 Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 125.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Zhengrong Lin, Hongye Li, Jinpeng Zhang, Xiaomei Pei, Zhao Chen, Zhenggang Cui, Binglei Song. (2023) Toroidal micelles formed in viscoelastic aqueous solutions of a double-tailed surfactant with two quaternary ammonium head groups. Soft Matter, 20 (4): (804-812). [PMID:38168697] [10.1039/D3SM01132A] |
| 2. Linlin Lv, Weiwei Luo, Yixiao Zhou, Tiechun Li, Quanping Diao, Pinyi Ma, Daqian Song. (2023) A highly sensitive ratiometric fluorescent probe based on fluorescein coumarin for detecting hydrazine in actual water and biological samples. LUMINESCENCE, 38 (2): (159-165). [PMID:36601685] [10.1002/bio.4435] |
| 3. He Jiajian, Cheng Kai, Lin Ruijun, Su Qiuping, Li Yong, Ma Zhiping, Wang Shaoshun, Gu Yuxin, Lin Xiaofeng, Lin Wenjing, Yi Guobin. (2022) Preparation and properties of a novel coating based on bismaleimides via Michael addition reaction. Journal of Coatings Technology and Research, 19 (6): (1731-1741). [PMID:] [10.1007/s11998-022-00644-8] |
| 4. Huixiang Li, Peifang Yan, Bo-Qing Xu, Z. Conrad Zhang. (2022) Oxygen affinity of transition metal cations: A coherent descriptor elucidating catalytic oxygenate transformations. JOURNAL OF CATALYSIS, [PMID:] [10.1016/j.jcat.2022.05.015] |
| 5. Kun WANG, Er-Fei DONG, Min FANG, Ting CHEN, Wei-Ju ZHU, Cun LI. (2022) Construction of ratio fluorescence sensor based on CdTe quantum dots and benzocoumarin-3-carboxylic acid for Hg2+ detection. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, [PMID:] [10.1016/j.cjac.2022.100070] |
| 6. Xiaojing Yang, Di-Feng Chen, Lin-Song Li, Xue-Jie Zhao, Mei-Xia Zhao. (2021) Mesoporous silica nanoparticles loaded with fluorescent coumarin-5-fluorouracil conjugates as mitochondrial-targeting theranostic probes for tumor cells. NANOTECHNOLOGY, 32 (45): (455101). [PMID:34340227] [10.1088/1361-6528/ac19d6] |
| 7. Fanyong Yan, Hao Zhang, Xing Li, Xiaodong Sun, Yingxia Jiang, Yali Cui. (2020) A fluorescein-coumarin based ratiometric fluorescent probe for detecting hydrazine and its real applications in cells imaging. TALANTA, [PMID:33298284] [10.1016/j.talanta.2020.121779] |
| 8. Yue Wang, Huan Feng, Haibo Li, Xinyi Yang, Hongmin Jia, Wenjun Kang, Qingtao Meng, Zhiqiang Zhang, Run Zhang. (2020) A Copper (II) Ensemble-Based Fluorescence Chemosensor and Its Application in the ‘Naked–Eye’ Detection of Biothiols in Human Urine. SENSORS, 20 (5): (1331). [PMID:32121408] [10.3390/s20051331] |
| 9. Xinfeng Cheng, Xiuping Ju, Hongmei Du, Yan Zhang, Jinsheng Zhao, Yu Xie. (2018) Synthesis and characterization of novel donor–acceptor type electrochromic polymers containing diketopyrrolopyrrole as an acceptor and propylenedioxythiophene or indacenodithiophene as a donor. RSC Advances, 8 (41): (23119-23129). [PMID:35540135] [10.1039/C8RA03570A] |
| 10. Linlin Yang, Jun Zhao, Xinling Yu, Ruilong Zhang, Guangmei Han, Renyong Liu, Zhengjie Liu, Tingting Zhao, Ming-Yong Han, Zhongping Zhang. (2018) Dynamic mapping of spontaneously produced H2S in the entire cell space and in live animals using a rationally designed molecular switch. ANALYST, 143 (8): (1881-1889). [PMID:29560968] [10.1039/C7AN01802A] |
| 11. Xueyi Sun, Yu Wang, Xiaofeng Zhang, Shihong Zhang, Zhao Zhang. (2015) A new coumarin based chromo-fluorogenic probe for selective recognition of cyanide ions in an aqueous medium. RSC Advances, 5 (117): (96905-96910). [PMID:] [10.1039/C5RA14500G] |
| 12. Binglei Song, Zonghui Xu, Xiaona Yu, Shuyi Chen, Shunan Li, Rongzhen Shi, Zhenggang Cui. (2015) Synthesis and Solution Properties of a Double-Tailed Quaternary Ammonium Surfactant with a Protrudent Head Group. JOURNAL OF SURFACTANTS AND DETERGENTS, 18 (6): (1081-1088). [PMID:] [10.1007/s11743-015-1738-y] |
| 13. Yue Huang, Yang Liu, Chuan Dong, Qi Zan, Feng Feng, Ruibing Wang, Shaomin Shuang. (2025) A Dual-Channel Fluorescent Probe with Mitochondria-Immobilization: Detecting Polarity and Viscosity During Mitophagy. BIOSENSORS & BIOELECTRONICS, [PMID:39954518] [10.1016/j.bios.2025.117246] |
| 14. Jun Li, Pingcong Lv, Hongli Ou, Xianling Yang, Youyi Chang, Yanli Li, Qian Zhou, Yimin Shan, Xianggui Chen, Xiaoqi Yu. (2025) A novel self-ratiometric fluorescent sensor of sodium alginate hydrogel bead doping with coumarin derivative with extremely acidic pH visual monitoring of fruit juice freshness. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:40089227] [10.1016/j.ijbiomac.2025.142099] |
| 15. Wenhui Lu, Chunli Ding, Mingshuo Zhu. (2024) Discrimination of coal geographical origins through HS-GC-IMS assisted with machine learning algorithms in larceny case. JOURNAL OF CHROMATOGRAPHY A, [PMID:39232421] [10.1016/j.chroma.2024.465330] |
| 16. Haohong Liu, Keyan Zheng, Qingwen Fang, Yunlian Shi, Ziyin Xie, Jie Wang, Xuliang Nie, Xugen Shi, Ruqiang Cui, Gang Sun, Dayong Peng. (2025) Synthesis of new pyrido[1,2-α] pyrimidinone derivatives and investigation of their insecticidal activity. JOURNAL OF MOLECULAR STRUCTURE, [PMID:] [10.1016/j.molstruc.2025.141712] |
| 17. Zhengrong Lin, Zutian Bi, Hongye Li, Xiaomei Pei, Zhao Chen, Zhenggang Cui, Binglei Song. (2024) Wormlike Micellar Glycerol Solutions Formed from a Double-Tailed Surfactant with Two Quaternary Ammonium Head Groups. LANGMUIR, [PMID:39254156] [10.1021/acs.langmuir.4c02024] |
| 18. Xingtian Zhang, Boyuan Yang, Yong Zhang, Xiaoyu Du, Liwei Hou, Tao Zhou, Hongtao Chu, Wenhui Ma. (2025) A Cell-Compatible Polyethylene Glycol Sensor for Dual-Mode Cu2+ Tracking: In Vivo Biosensing and Smartphone-Based High-Sensitivity Detection In Vitro. JOURNAL OF APPLIED POLYMER SCIENCE, [PMID:] [10.1002/app.57592] |
| 19. Jiahua Lu, Chunmu Wang, Yusen Wu, Jie Zhu, Jujun Ruan. (2025) Recycling of waste crystalline silicon photovoltaic modules: Efficient decapsulation and silver extraction using environmental-friendly reagents and deep eutectic solvents. SOLAR ENERGY MATERIALS AND SOLAR CELLS, [PMID:] [10.1016/j.solmat.2025.113882] |
| 20. Xingtian Zhang, Boyuan Yang, Yong Zhang, Xiaoyu Du, Liwei Hou, Tao Zhou, Hongtao Chu, Wenhui Ma. (2025) A dual-responsive polyacrylamide sensor for colorimetric and fluorescent detection of Cu2+. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:40889449] [10.1016/j.saa.2025.126891] |
| 21. Fanda Feng, Lingqian Kong, Hongmei Du, Jinsheng Zhao, Junhong Zhang. (2018) Donor-Acceptor-Type Copolymers Based on 3,4-Propylenedioxy-thiophene and 5,6-Difluorobenzotriazole: Synthesis and Electrochromic Properties. Polymers, 10 (4): (427). [PMID:30966462] [10.3390/polym10040427] |
| 22. Weixia Zhu, Zhenya Wang, Youming Kou, Peixin Liu, Haoran Wu. (2025) High-performance donor-acceptor stenhouse adduct sensors with multi-stimuli response for efficient metal ion detection. NEW JOURNAL OF CHEMISTRY, [PMID:] [10.1039/D5NJ00434A] |
| 23. Qinglong Zhang, Wen Zheng, Wangyang Lu, Wenxing Chen. (2026) Screening of Imidazole-Based Catalysts Through Model Reactions for Efficient Polymerization of AB-Type Polybenzoxazole Monomers and Investigation of the Catalytic Mechanism. POLYMER ENGINEERING AND SCIENCE, [PMID:] [10.1002/pen.70462] |