DL-システイン - Moligand™,≥97% , CAS No.3374-22-9

CAS: 3374-22-9 Cat. No.: C110437 分子式: C₃H₇NO₂S 分子量: 121.16 Beilstein Registry Number: 1721406 EC番号: 222-160-2

GRADE & PURITY Moligand™, ≥97%

Synonyms

SR-01000944791 | Tox21_111766_1 | [35s]cysteine | A821916 | CCRIS 8598 | FD21272 | NCGC00248803-03 | SY009625 | d,l-cysteine | CAS-3374-22-9 | Zystein | CAS_5862 | L-Cysteine-13C3 | NSC 63864 | CHEBI:15356 | Hcys | UNII-5CM45Q5YAF | AB02703 | L-CYSTEINE (

Storage

2-8℃で保管、アルゴン充填

Shipped In

濡れた氷

概要

製品の説明

システインは、メチオニンの十分な量が利用可能である場合、通常の生理的条件下で人体によって合成することができる非必須アミノ酸である。システインは、一般的に食品および製薬業界の前駆体として使用されます。システインはベーキングのための加工助剤として、タバコの添加物として、また肉味の準備で使用される。

製品用途
NMDAアゴニストで、高濃度ではキスクワレート受容体のアゴニストとなる。

Specifications

同義語

SR-01000944791 | Tox21_111766_1 | [35s]cysteine | A821916 | CCRIS 8598 | FD21272 | NCGC00248803-03 | SY009625 | d,l-cysteine | CAS-3374-22-9 | Zystein | CAS_5862 | L-Cysteine-13C3 | NSC 63864 | CHEBI:15356 | Hcys | UNII-5CM45Q5YAF | AB02703 | L-CYSTEINE (

仕様と純度

Moligand™, ≥97%

生化学的・生理学的メカニズム

NMDAアゴニストで、高濃度ではキスクワレート受容体のアゴニストとなる。

保管条件

2-8℃で保管、アルゴン充填

入荷

濡れた氷

等級

Moligand™

純度

≥97%

名前と識別子

• パブケム・シド: 508810488
• パブケム・シド・ウル: https://pubchem.ncbi.nlm.nih.gov/substance/508810488
• カノニカル・スマイル: C(C(C(=O)O)N)S
• IUPAC Name: 2-amino-3-sulfanylpropanoic acid
• InChIKey: XUJNEKJLAYXESH-UHFFFAOYSA-N
• INCHI: 1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)
• 異性体SMILES: C(C(C(=O)O)N)S
• WGKドイツ: 3
• 分子量: 121.16
• Beilstein: 1721406
• Reaxy-Rn: 1721406
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1721406&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • 分類 Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Cysteine and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• 分類: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Cysteine and derivatives
• Alternative Parents: Alpha amino acids Amino acids Monocarboxylic acids and derivatives Carboxylic acids Alkylthiols Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Cysteine or derivatives - Alpha-amino acid - Amino acid - Alkylthiol - Carboxylic acid - Monocarboxylic acid or derivatives - Organic nitrogen compound - Hydrocarbon derivative - Primary amine - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic oxide - Primary aliphatic amine - Organopnictogen compound - Carbonyl group - Amine - Organic oxygen compound - Aliphatic acyclic compound
• 説明: This compound belongs to the class of organic compounds known as cysteine and derivatives. These are compounds containing cysteine or a derivative thereof resulting from reaction of cysteine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
• External Descriptors: sulfur-containing amino acid - alpha-amino acid

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

関連ターゲット（人間）

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HepG2 (196354 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LMNA Tbio Prelamin-A/C (36751 Activities)

Discover Target: LMNA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

関連ターゲット（非人間）

Adam17 ADAM17 (14 Activities)

Discover Target: Adam17

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Luciferin 4-monooxygenase (66902 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)

Discover Target: ffp

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用メカニズム

化学的性質と物理的性質

• 溶解度: Soluble in water (partly), 1 N HCl (25 mg/ml), ethanol, and acetic acid. Insoluble in acetone.
• 感度: light sensitive;Air sensitive;Moisture sensitive
• 融点（°C）: 225°C
• 分子量: 121.160 g/mol
• XLogP3: -2.500
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 121.02 Da
• Monoisotopic Mass: 121.02 Da
• Topological Polar Surface Area: 64.300 Ų
• Heavy Atom Count: 7
• Formal Charge: 0
• Complexity: 75.300
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

参考文献

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2. Xuejing Wang, Yinyan Yuan, YiXiao Sun, Xue Liu, Mingze Ma, Renyin Zhang, Feng Shi.  (2022)  One-step facile preparation of carbon dots with high fluorescence quantum yield and application in rapid latent fingerprint detection.  RSC Advances,  12  (42): (27199-27205).  [PMID:36276032] [10.1039/D2RA05397G]

3. Ruihong Yao, Zhijian Li, Panpan Huo, Congcong Gong, Gang Liu, Chunhong Zheng, Shouzhi Pu.  (2022)  L-histidine functionalized ZiF-8 with aggregation-induced emission for detection of tetracycline.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:35759934] [10.1016/j.saa.2022.121546]

4. Shuting Chen, Weijia Wang, Shaohua Xu, Caili Fu, Shuyi Ji, Fang Luo, Cuiying Lin, Bin Qiu, Zhenyu Lin.  (2021)  Single nanoparticle identification coupled with auto-identify algorithm for rapid and accurate detection of L-histidine.  ANALYTICA CHIMICA ACTA,      [PMID:34753576] [10.1016/j.aca.2021.339162]

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6. Jian Zhang, Yanqing Miao, Zhao Cheng, Lingling Liang, Xiaoya Ma, Chunye Liu.  (2020)  A paper-based colorimetric assay system for sensitive cysteine detection using a fluorescent probe.  ANALYST,  145  (5): (1878-1884).  [PMID:31971166] [10.1039/C9AN02271F]

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8. Guo-Cheng Han, Xiaorui Su, Jiating Hou, Annaleizle Ferranco, Xiao-Zhen Feng, Ruosheng Zeng, Zhencheng Chen, Heinz-Bernhard Kraatz.  (2018)  Disposable electrochemical sensors for hemoglobin detection based on ferrocenoyl cysteine conjugates modified electrode.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2018.11.042]

9. Qing Xiong, Jing Jin, Liqiong Lv, Zhisi Bu, Shengqiang Tong.  (2018)  Chiral ligand exchange countercurrent chromatography: Enantioseparation of amino acids.  JOURNAL OF SEPARATION SCIENCE,  41  (6): (1479-1488).  [PMID:29323783] [10.1002/jssc.201701117]

10. Jianping Li, Xionghui Ma, Mengxi Li, Yun Zhang.  (2017)  Does polysaccharide is an idea template selection for glycosyl imprinting?.  BIOSENSORS & BIOELECTRONICS,      [PMID:28818784] [10.1016/j.bios.2017.08.004]

11. Wang Shulong, Huang Wenfang, Lin Qingyan, Feng Yinyin, Wei Qingmin, Xu Jiayao, Wang Rong, Luo Zhihui.  (2024)  Design and synthesis of a novel chiral photoacoustic probe and accurate imaging detection of hydrogen peroxide in vivo.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,      [PMID:39078455] [10.1007/s00216-024-05463-x]

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