DL-Mevalonolactone - ≥98% , CAS No.674-26-0

CAS: 674-26-0 Cat. No.: D304342 分子式: C₆H₁₀O₃ 分子量: 130.14 EC番号: 211-615-0

グレード＆純度 ≥98%

Synonyms

LMFA07040003 | 1RJ06DC41B | MEVALONOLACTONE, DL- | Mevalonic acid .delta.-lactone | 009D7F12-69C6-4BBF-A66D-12BA84648C72 | AS-65830 | HMS2097E22 | NCGC00179453-01 | .beta.-Hydroxy-.beta.-methyl-.delta.-valerolactone | 2H-PYRAN-2-ONE, TETRAHYDRO-4-HYDROXY-

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

概要

Alkaline hydrolysis of mevalonolactone gives mevalonate. Mevalonate is a precursor of farnesyl and geranylgeranyl pyrophosphates. These pyrophosphates are required for protein prenylation. 

Application

(±)-Mevalonolactone is used to:

• study the effect of statin on the prenylation of Ras and Rho GTPases

• analyse the isoprenoid biosynthesis pathways in Listeria monocytogenes

• study the the effects of statins on proliferation and migration of HUVECs (HGF-induced human umbilical vein endothelial cells) 

仕様

同義語

LMFA07040003 | 1RJ06DC41B | MEVALONOLACTONE, DL- | Mevalonic acid .delta.-lactone | 009D7F12-69C6-4BBF-A66D-12BA84648C72 | AS-65830 | HMS2097E22 | NCGC00179453-01 | .beta.-Hydroxy-.beta.-methyl-.delta.-valerolactone | 2H-PYRAN-2-ONE, TETRAHYDRO-4-HYDROXY-

仕様と純度

≥98%

保管条件

Store at -20°C,Argon charged

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

純度

≥98%

名前と識別子

パブケム・シド

508810493

パブケム・シド・ウル

https://pubchem.ncbi.nlm.nih.gov/substance/508810493

カノニカル・スマイル

CC1(CCOC(=O)C1)O

IUPAC Name

4-hydroxy-4-methyloxan-2-one

InChIKey

JYVXNLLUYHCIIH-UHFFFAOYSA-N

INCHI

1S/C6H10O3/c1-6(8)2-3-9-5(7)4-6/h8H,2-4H2,1H3

異性体SMILES

CC1(CCOC(=O)C1)O

分子量

130.14

Reaxy-Rn

80960

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=80960&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 分類 Lactones
      • Subclass Delta valerolactones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 分類: Lactones
• Subclass: Delta valerolactones
• Intermediate Tree Nodes: Not available
• Direct Parent: Delta valerolactones
• Alternative Parents: Oxanes Tertiary alcohols Carboxylic acid esters Oxacyclic compounds Monocarboxylic acids and derivatives Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Delta_valerolactone - Delta valerolactone - Oxane - Tertiary alcohol - Carboxylic acid ester - Oxacycle - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic heteromonocyclic compound
• 説明: This compound belongs to the class of organic compounds known as delta valerolactones. These are cyclic organic compounds containing an oxan-2- one moiety.
• External Descriptors: Lactones

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

作用メカニズム

化学的性質と物理的性質

• 感度: Moisture & heat sensitive
• 屈折率: 1.48
• 引火点（°F）: 235.4 °F
• 引火点（°C）: 113 °C
• 沸点（°C）: 150 °C/5 mmHg
• 融点（°C）: 28 °C
• 分子量: 130.139 g/mol
• XLogP3: -0.300
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 130.063 Da
• Monoisotopic Mass: 130.063 Da
• Topological Polar Surface Area: 46.500 Ų
• Heavy Atom Count: 9
• Formal Charge: 0
• Complexity: 132.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1