DLinDMA - ≥98% , CAS No.871258-12-7

CAS: 871258-12-7 Cat. No.: D413024 分子式: C₄₁H₇₇NO₂ 分子量: 616.16

GRADE & PURITY ≥98%

Synonyms

1-Propanamine, N,N-dimethyl-2,3-bis((9Z,12Z)-9,12-octadecadien-1-yloxy)- | NFQBIAXADRDUGK-KWXKLSQISA-N | 1,2-dilinoleyloxy-n,n-dimethyl-3-aminopropane | N,N-dimethyl-2,3-bis[(9Z,12Z)-octadeca-9,12-dienoxy]propan-1-amine | 1,2-dilinoleyloxy-3-dimethylamino

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Application

Drug Delivery, Surface Modification, PEGylation of Protein, Peptide & Oligo

概要

Information

DLinDMA is an ionizable cationic lipid for siRNA delivery. DLinDMA is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark.

Specifications

同義語

1-Propanamine, N,N-dimethyl-2,3-bis((9Z,12Z)-9,12-octadecadien-1-yloxy)- | NFQBIAXADRDUGK-KWXKLSQISA-N | 1,2-dilinoleyloxy-n,n-dimethyl-3-aminopropane | N,N-dimethyl-2,3-bis[(9Z,12Z)-octadeca-9,12-dienoxy]propan-1-amine | 1,2-dilinoleyloxy-3-dimethylamino

仕様と純度

≥98%

生化学的・生理学的メカニズム

DLinDMA is an ionizable cationic lipid for siRNA delivery. DLinDMA is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark.

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

純度

≥98%

名前と識別子

• パブケム・シド: 528771844
• カノニカル・スマイル: CCCCCC=CCC=CCCCCCCCCOCC(CN(C)C)OCCCCCCCCC=CCC=CCCCCC
• IUPAC Name: N,N-dimethyl-2,3-bis[(9Z,12Z)-octadeca-9,12-dienoxy]propan-1-amine
• InChIKey: NFQBIAXADRDUGK-KWXKLSQISA-N
• INCHI: 1S/C41H77NO2/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-43-40-41(39-42(3)4)44-38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h13-16,19-22,41H,5-12,17-18,23-40H2,1-4H3/b15-13-,16-14-,21-19-,22-20-
• 異性体SMILES: CCCCC/C=C\C/C=C\CCCCCCCCOCC(CN(C)C)OCCCCCCCC/C=C\C/C=C\CCCCC
• 分子量: 616.16
• Reaxy-Rn: 29349580
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29349580&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • 分類 Organonitrogen compounds
      • Subclass Amines
        • Level5 Tertiary amines
          • Level6 Trialkylamines

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• 分類: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Tertiary amines
• Direct Parent: Trialkylamines
• Alternative Parents: Dialkyl ethers Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Tertiary aliphatic amine - Ether - Dialkyl ether - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aliphatic acyclic compound
• 説明: This compound belongs to the class of organic compounds known as trialkylamines. These are organic compounds containing a trialkylamine group, characterized by exactly three alkyl groups bonded to the amino nitrogen.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

化学的性質と物理的性質

• 分子量: 616.100 g/mol
• XLogP3: 14.500
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 35
• Exact Mass: 615.595 Da
• Monoisotopic Mass: 615.595 Da
• Topological Polar Surface Area: 21.700 Ų
• Heavy Atom Count: 44
• Formal Charge: 0
• Complexity: 651.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 4
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 4
• Covalently-Bonded Unit Count: 1