DPP-IV-IN-1 - ≥98% , CAS No.625110-37-4

CAS: 625110-37-4 Cat. No.: D646861 分子式: C₁₁H₁₈FN₃O₂ 分子量: 243.28

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

概要

DPP-IV-IN-1 is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV) , a highly specific serine protease , with an IC 50 of 4.6 nM.

In Vivo

DPP-IV-IN-1 (0.1 and 0.3 mg/kg, p.o.) reduces the increase in plasma glucose beginning 30 min after glucose loading, and significantly suppresses hyperglycemia at the dose of 0.3 mg/kg in a rat model of obesity and impaired glucose tolerance. The effect is based on its inhibitory effect on plasma DPP-IV activity . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Specifications

仕様と純度

≥98%

生化学的・生理学的メカニズム

DPP-IV-IN-1 is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV) , a highly specific serine protease , with an IC 50 of 4.6 nM.

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

INHIBITOR

純度

≥98%

名前と識別子

• 分子量: 243.28

化学的性質と物理的性質

• 溶解度: DMSO : 125 mg/mL (513.81 mM; Need ultrasonic)