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DRB18 - ≥98% , CAS No.D414435
注文可能
GRADE & PURITY ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Why this grade
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
概要
Information
DRB18 DRB18 is a pan-GLUT (glucose transporters) inhibitor that inhibits growth and proliferation in several different cancer types with IC50 high nM range.
Targets
GLUT
In vitro
DRB18 inhibits growth and proliferation in about 90% of the 60 different cancer cell lines in 9 major cancer types. DRB18 treatment leads to significant changes in glucose-based metabolism in A549 lung cancer cells, including cell death via ER/oxidative stress and necrosis.
In vivo
DRB18 (10 mg/kg) treatment thrice a week significantly reduces growth in Xenograft A549 tumors.
Specifications
仕様と純度
≥98%
生化学的・生理学的メカニズム
DRB18 is a pan-GLUT (glucose transporters) inhibitor that inhibits growth and proliferation in several different cancer types with IC50 high nM range.
保管条件
Store at -20°C
入荷
Ice chest + Ice pads
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
純度
≥98%
製品の性質
| ALogP | 5.767 |
|---|---|
| HBD数 | 4 |
| 回転可能な結合 | 6 |
名前と識別子
| カノニカル・スマイル | CC1=CC=C(CNC2=C(NCC3=CC(=C(C)C=C3)O)C=C(Cl)C=C2)C=C1O |
|---|---|
| 分子量 | 382.88 |
| Reaxy-Rn | 36374407 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=36374407&ln= |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
証明書（CoA、COO、BSE/TSEと分析図）
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
化学的性質と物理的性質
| 溶解度 | Solubility (25°C) In vitro DMSO: 76 mg/mL (198.49 mM); Ethanol: 76 mg/mL (198.49 mM); Water: Insoluble; |
|---|---|
| DMSO（mg / mL） 最大溶解度 | 76 |
| DMSO（mM） 最大溶解度 | 198.495612202257 |
| 水（mg / mL） 最大溶解度 | ＜1 |
ソリューション計算機
レビュー
顧客レビュー
よくある質問
What is the purity of this product?
This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is D414435, the molecular formula is C22H23ClN2O2, and the molecular weight is 382.88 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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