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340,000+ 研究の概要 · Triple ISO certified · COA & SDS すべての製品に適用 · 在庫品は当日出荷

E-3810 - Moligand™, ≥98% , Fibroblast growth factor receptor 2 inhibitor, CAS No.1058137-23-7, Fibroblast growth factor receptor 2 inhibitor

CAS: 1058137-23-7 Cat. No.: E127640 分子式: C26H25N3O4 分子量: 443.49
COA
E-3810 - Moligand™, ≥98% CAS No(1058137-23-7) by Aladdin Scientific
注文可能
グレード＆純度 Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
1,13-dimethyl-10-(3-methyl-2-butenyl)-(1R,9R,13R)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol(Pentazocine) | LUCITANIB [WHO-DD] | Pentobarbitone (VAN) | 6-((7-((1-aminocyclopropyl)methoxy)-6-methoxyquinolin-4-yl)oxy)-N-methyl-1-naphthamide | AMY
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
サイズ
USA
ドイツ (EU)*
価格
個数
1mg
E127640-1mg
3 在庫あり
—

$69.90

$104.90
保存 $35.00 (33.37%)
5mg
E127640-5mg
3 在庫あり
—

$89.90

$134.90
保存 $45.00 (33.36%)
10mg
E127640-10mg
2 在庫あり
—

$116.90

$175.90
保存 $59.00 (33.54%)
25mg
E127640-25mg
2 在庫あり
—

$151.90

$227.90
保存 $76.00 (33.35%)
50mg
E127640-50mg
2 在庫あり
—

$256.90

$385.90
保存 $129.00 (33.43%)
100mg
E127640-100mg
受注生産 · 8～12週間

$436.90

$655.90
保存 $219.00 (33.39%)
Enter a quantity for the sizes you want to add.
バルク / カスタム
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SDS
Safety data
COA
Certificate
DS
データシート
SP
仕様書
仕様 製品の性質 名前と識別子 詳細データ Taxonomic Classification 3 D構造 関連ターゲット（人間） 証明書（CoA、COO、BSE/TSEと分析図） 化学的性質と物理的性質 ソリューション計算機 レビュー

仕様

同義語
1,13-dimethyl-10-(3-methyl-2-butenyl)-(1R,9R,13R)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol(Pentazocine) | LUCITANIB [WHO-DD] | Pentobarbitone (VAN) | 6-((7-((1-aminocyclopropyl)methoxy)-6-methoxyquinolin-4-yl)oxy)-N-methyl-1-naphthamide | AMY
仕様と純度
Moligand™, ≥98%
生化学的・生理学的メカニズム

E-3810, a novel dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs) with antiangiogenic activity. VEGFR/FGFR dual kinase inhibitor E-3810 inhibits VEGFR-1, -2

保管条件
Store at -20°C
入荷
Ice chest + Ice pads
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
等級
Moligand™
アクションタイプ
INHIBITOR
作用メカニズム
Fibroblast growth factor receptor 2 inhibitor
純度
≥98%
製品の性質
ALogP
3.6
名前と識別子
パブケム・シド
504769941
パブケム・シド・ウル
https://pubchem.ncbi.nlm.nih.gov/substance/504769941
カノニカル・スマイル
CNC(=O)C1=CC=CC2=C1C=CC(=C2)OC3=C4C=C(C(=CC4=NC=C3)OCC5(CC5)N)OC
IUPAC Name
6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-methylnaphthalene-1-carboxamide
InChIKey
CUDVHEFYRIWYQD-UHFFFAOYSA-N
INCHI
1S/C26H25N3O4/c1-28-25(30)19-5-3-4-16-12-17(6-7-18(16)19)33-22-8-11-29-21-14-24(23(31-2)13-20(21)22)32-15-26(27)9-10-26/h3-8,11-14H,9-10,15,27H2,1-2H3,(H,28,30)
異性体SMILES
CNC(=O)C1=CC=CC2=C1C=CC(=C2)OC3=C4C=C(C(=CC4=NC=C3)OCC5(CC5)N)OC
分子量
443.49
Reaxy-Rn
18478470
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18478470&ln=

詳細データ

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
分類Naphthalenes
SubclassNaphthalenecarboxylic acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentNaphthalenecarboxamides
Alternative Parents Diarylethers  Quinolines and derivatives  Anisoles  Alkyl aryl ethers  Pyridines and derivatives  Heteroaromatic compounds  Secondary carboxylic acid amides  Amino acids and derivatives  Azacyclic compounds  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents 1-naphthalenecarboxamide - Diaryl ether - Quinoline - Anisole - Alkyl aryl ether - Pyridine - Heteroaromatic compound - Amino acid or derivatives - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid derivative - Ether - Azacycle - Organoheterocyclic compound - Organic oxygen compound - Primary aliphatic amine - Amine - Hydrocarbon derivative - Organic nitrogen compound - Organic oxide - Organonitrogen compound - Organooxygen compound - Primary amine - Organopnictogen compound - Aromatic heteropolycyclic compound
説明This compound belongs to the class of organic compounds known as naphthalenecarboxamides. These are compounds containing a naphthalene moiety, which bears a carboxylic acid amide group at one or more positions. Naphthalene is a bicyclic compound that is made up of two fused benzene rings.
External Descriptors aromatic ether - quinolines - primary amino compound - cyclopropanes - naphthalenecarboxamide
3 D構造
インタラクティブ化学構造モデル





関連ターゲット（人間）
DDR1 Tchem Epithelial discoidin domain-containing receptor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RET Tclin Proto-oncogene tyrosine-protein kinase receptor Ret (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FLT4 Tclin Vascular endothelial growth factor receptor 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FGFR1 Tclin Fibroblast growth factor receptor 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDGFRA Tclin Platelet-derived growth factor receptor alpha (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDGFRB Tclin Platelet-derived growth factor receptor beta (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FLT1 Tclin Vascular endothelial growth factor receptor 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KDR Tclin Vascular endothelial growth factor receptor 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KIT Tclin Mast/stem cell growth factor receptor Kit (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
証明書（CoA、COO、BSE/TSEと分析図）
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate Type日付商品
L2420505L2420505Certificate of AnalysisSep 21, 2026 E127640
B2603038B2603038Certificate of AnalysisFeb 25, 2026 E127640
L2117112L2117112Certificate of AnalysisJul 15, 2025 E127640
L2117113L2117113Certificate of AnalysisJul 15, 2025 E127640
L2117128L2117128Certificate of AnalysisJul 15, 2025 E127640
L2117319L2117319Certificate of AnalysisJul 15, 2025 E127640
L2117320L2117320Certificate of AnalysisJul 15, 2025 E127640
L2117321L2117321Certificate of AnalysisJul 15, 2025 E127640
化学的性質と物理的性質
溶解度DMSO
分子量443.500 g/mol
XLogP33.600
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass443.185 Da
Monoisotopic Mass443.185 Da
Topological Polar Surface Area95.700 Ų
Heavy Atom Count33
Formal Charge0
Complexity686.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
ソリューション計算機
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