eIF4A3-IN-18 , CAS No.1402931-84-3

CAS: 1402931-84-3 Cat. No.: E650559 分子式: C₂₉H₂₈N₂O₆ 分子量: 500.54

Storage

Store at 2-8°C,Protected from light,Desiccated

Shipped In

Wet ice

概要

eIF4A3-IN-18 (compound 74) is a silvestrol analogue. eIF4A3-IN-18 interferes the assembling of eIF4F translation complex with EC 50 values of 0.8, 35 and 2 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-18 also has cytotoxicity to RMPI-8226 cells with an LC 50 of 0.06 nM. eIF4A3-IN-18 can be used for the research of human cancer pathogenesis.

Form:Solid

仕様

生化学的・生理学的メカニズム

eIF4A3-IN-18 (compound 74) is a silvestrol ( HY-13251 ) analogue. eIF4A3-IN-18 interferes the assembling of eIF4F translation complex with EC 50 values of 0.8, 35 and 2 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-18 a

保管条件

Store at 2-8°C,Protected from light,Desiccated

入荷

Wet ice

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

名前と識別子

カノニカル・スマイル

COC1=CC=C([C@@]23OC4=CC(C#N)=CC(OC)=C4[C@]2(O)[C@@H]([C@@H]([C@H]3C5=CC=CC=C5)C(N(C)C)=O)O)C=C1

分子量

500.54

よくある質問

How should this product be stored?

Store at 2–8 °C, protected from light, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1402931-84-3, the molecular formula is C29H28N2O6, and the molecular weight is 500.54 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.