Emavusertib phosphate (CA-4948 phosphate) is the phosphate salt form of Emavusertib. Emavusertib phosphate is an orally active inhibitor for IRAK4 ( IC 50 =57 nM) and FLT3. Emavusertib phosphate inhibits NF-κB and MyD88 signaling pathways, reduces the generation of pro-inflammatory cytokines like IL-6 and IL-10 , thereby exhibiting anti-inflammatory and anti-proliferative activities against cancer cells, leading to cell apoptosis. Emavusertib phosphate exhibits antitumor activity in mouse model.
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How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 2376399-38-9, the molecular formula is C24H28N7O9P, and the molecular weight is 589.49 g/mol.
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