Enfumafungin - ≥99% , CAS No.260979-95-1

CAS: 260979-95-1 Cat. No.: E649391 分子式: C₃₈H₆₀O₁₂ 分子量: 708.88

GRADE & PURITY ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

概要

Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus ) and does not inhibit the growth of Bacillus subtilis

In Vitro

Enfumafungin (24-48 h) has MICs of less than 0.5 μg/mL against the Candida and Aspergillus species tested and it is inactive against Cryptococcus , including the decapsulated form (MY2062). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Enfumafungin (50-200 mg/kg; i.p. twice daily for 2 days) produces a significant decrease in the number of c.f.u. in kidneys of mice challenged with C. albicans , with an ED 90 of 90 mg/kg . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:(1,3)-beta-D-glucan synthase

Specifications

仕様と純度

≥99%

生化学的・生理学的メカニズム

Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specifi

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

INHIBITOR

純度

≥99%

名前と識別子

• 分子量: 708.88

化学的性質と物理的性質

• 溶解度: DMSO : 100 mg/mL (141.07 mM; Need ultrasonic)