Enoxolone - Moligand™, 10mM in DMSO , Inhibitor of hydroxysteroid 11-beta dehydrogenase 1;Inhibitor of hydroxysteroid 11-beta dehydrogenase 2, CAS No.471-53-4, Inhibitor of hydroxysteroid 11-beta dehydrogenase 1;Inhibitor of hydroxysteroid 11-beta dehydrogenase 2

CAS: 471-53-4 Cat. No.: E407903 分子式: C₃₀H₄₆O₄ 分子量: 470.68 Beilstein Registry Number: 2229654 EC番号: 207-444-6

グレード＆純度 Moligand™, 10mM in DMSO

Synonyms

Glycyrrhetin | Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3β,20β)-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Information

Enoxolone Enoxolone (Glycyrrhetin) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥95%

仕様

同義語

Glycyrrhetin | Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3β,20β)-

仕様と純度

Moligand™, 10mM in DMSO

生化学的・生理学的メカニズム

Enoxolone (Glycyrrhetin) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

INHIBITOR

作用メカニズム

Inhibitor of hydroxysteroid 11-beta dehydrogenase 1;Inhibitor of hydroxysteroid 11-beta dehydrogenase 2

名前と識別子

異性体SMILES

C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)(C)C(=O)O

WGKドイツ

3

RTECS

RK0180000

分子量

470.68

Beilstein

2229654

Reaxy-Rn

3041142

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3041142&ln=

関連ターゲット（人間）

HSD11B2 Tchem Corticosteroid 11-beta-dehydrogenase isozyme 2 (0 Activities)

Discover Target: HSD11B2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HSD11B1 Tclin Corticosteroid 11-beta-dehydrogenase isozyme 1 (0 Activities)

Discover Target: HSD11B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (0 Activities)

Discover Target: SLCO1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (0 Activities)

Discover Target: SLCO1B3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

化学的性質と物理的性質

• 比旋光度［α］: 162 ° (C=1, MeOH)
• 融点（°C）: 292-295°C