EP1013 - 10mM in DMSO , CAS No.223568-55-6

CAS: 223568-55-6 Cat. No.: E654834 分子式: C₁₈H₂₃FN₂O₆ 分子量: 382.38 PubChem CID: 9907987

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

EP1013 (F1013) is a broad-spectrum caspase selective inhibitor, used in the research of type 1 diabetes

In Vivo

EP1013 (1, 3, 10 mg/kg) significantly improves marginal islet mass function. Two animals in the 10 mg/kg EP1013 treatment group exhibit primary islet graft nonfunction, but the diabetes reversal\nrate for this group is not significantly different from the 3 mg/kg EP1013, 1 mg/kg EP1013, or 10 mg/kg zVAD groups. EP1013 therapy enhances functional syngeneic islet mass and promotes longevity of islet graft function . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:Caspase

Specifications

仕様と純度

10mM in DMSO

生化学的・生理学的メカニズム

EP1013 (F1013) is a broad-spectrum caspase selective inhibitor, used in the research of type 1 diabetes.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

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アクションタイプ

INHIBITOR

名前と識別子

• 異性体SMILES: CC(C)[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)CF)NC(=O)OCC1=CC=CC=C1
• PubChem CID: 9907987
• MeSH用語: benzyloxycarbonyl-valyl-aspartic acid fluoromethyl ketone;EP1013;F573 compound;MX1013;N-benzyloxycabonyl-Val Asp-fluoromethyl ketone;Z-VD-FMK;zVD-FMK
• 分子量: 382.38