Epitinib succinate - ≥99% , CAS No.2252334-12-4

CAS: 2252334-12-4 Cat. No.: E649053 分子式: C₂₈H₃₂N₆O₆ 分子量: 548.59 PubChem CID: 135379897

グレード＆純度 ≥99%

Synonyms

Epitinib (succinate) | 2252334-12-4 | Epitinib succinate | butanedioic acid;4-ethyl-N-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]piperazine-1-carboxamide | SCHEMBL20561708 | 4-Ethyl-N-(4-((3-ethynylphenyl)amino)-7-methoxy-6-quinazolinyl)-1-piperazinec

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

概要

Epitinib succinate is an orally active and selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) designed for optimal brain penetration. Epitinib succinate can be used for the research of cancer

In Vitro

Epitinib succinate is an orally active and selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) designed for optimal brain penetration . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:EGFR

仕様

同義語

Epitinib (succinate) | 2252334-12-4 | Epitinib succinate | butanedioic acid;4-ethyl-N-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]piperazine-1-carboxamide | SCHEMBL20561708 | 4-Ethyl-N-(4-((3-ethynylphenyl)amino)-7-methoxy-6-quinazolinyl)-1-piperazinec

仕様と純度

≥99%

生化学的・生理学的メカニズム

Epitinib succinate is an orally active and selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) designed for optimal brain penetration. Epitinib succinate can be used for the research of cancer.

保管条件

Store at 2-8°C,Desiccated

入荷

Wet ice

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

INHIBITOR

純度

≥99%

名前と識別子

カノニカル・スマイル

CCN1CCN(CC1)C(=O)NC2=C(C=C3C(=C2)C(=NC=N3)NC4=CC=CC(=C4)C#C)OC.C(CC(=O)O)C(=O)O

IUPAC Name

butanedioic acid;4-ethyl-N-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]piperazine-1-carboxamide

InChIKey

HISXHQFAOANCJX-UHFFFAOYSA-N

INCHI

1S/C24H26N6O2.C4H6O4/c1-4-17-7-6-8-18(13-17)27-23-19-14-21(22(32-3)15-20(19)25-16-26-23)28-24(31)30-11-9-29(5-2)10-12-30;5-3(6)1-2-4(7)8/h1,6-8,13-16H,5,9-12H2,2-3H3,(H,28,31)(H,25,26,27);1-2H2,(H,5,6)(H,7,8)

異性体SMILES

CCN1CCN(CC1)C(=O)NC2=C(C=C3C(=C2)C(=NC=N3)NC4=CC=CC(=C4)C#C)OC.C(CC(=O)O)C(=O)O

代替CAS番号

2252334-12-4

PubChem CID

135379897

分子量

548.59

化学的性質と物理的性質

• 溶解度: DMSO : 12.5 mg/mL (22.79 mM; ultrasonic and warming and heat to 60°C) H2O : <0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)