3,3'-(Methylimino)-dipropionic Acid Dimethyl Ester FAQs

3,3'-(Methylimino)-dipropionic acid dimethyl ester is a bifunctional nitrogen-containing diester that serves as a versatile synthetic intermediate in organic and medicinal chemistry research.

Chemical Name

3,3'-(Methylimino)-dipropionic acid dimethyl ester

SKU / Catalog Number

M694162

Functional Groups

Tertiary amine and two methyl ester groups

Molecular Framework

Symmetrical diester built on a methylamino nitrogen center flanked by two propionic acid methyl ester arms

Supplier

Aladdin Scientific

Typical Application

Synthetic intermediate for chelating agents, ligands, and pharmaceutical building blocks

What Is 3,3'-(Methylimino)-dipropionic Acid Dimethyl Ester?

3,3'-(Methylimino)-dipropionic acid dimethyl ester is an organic compound featuring a central tertiary amine nitrogen (N-methyl) flanked by two beta-propionic acid methyl ester chains. This symmetrical structure gives the molecule dual electrophilic ester handles alongside a nucleophilic/coordinative amine center, making it a versatile building block in synthetic chemistry.

The compound is catalogued under Aladdin Scientific SKU M694162. It is related structurally to iminodiacetic acid derivatives but with extended propionate arms and methyl ester protection, which modulates its reactivity and solubility profile relative to shorter-chain analogues.

Storage, Handling, and Safety Considerations

As with most ester-containing reagents, 3,3'-(Methylimino)-dipropionic acid dimethyl ester should be stored in a cool, dry, well-ventilated area away from moisture and strong bases, which can promote ester hydrolysis. Sealed containers under inert atmosphere (nitrogen or argon) are recommended for long-term stability.

Standard laboratory personal protective equipment (PPE) — including chemical-resistant gloves, safety goggles, and a lab coat — should be worn when handling this compound. Work in a fume hood is advisable to minimize inhalation of vapors. Consult the Safety Data Sheet (SDS) provided by Aladdin Scientific for product-specific hazard classifications, first-aid measures, and disposal guidelines before use.

Note: Specific GHS hazard categories and pictograms for M694162 should be confirmed against the current Aladdin SDS.

Research Applications and Reactivity

The dual methyl ester groups of this compound are amenable to a range of transformations including saponification (hydrolysis to the diacid), aminolysis to form diamides, and reduction to amino alcohols. The tertiary amine center can coordinate to metal ions, making hydrolyzed or partially modified forms of this compound potentially useful as ligand precursors for metal chelation or coordination chemistry.

In medicinal chemistry, beta-amino ester scaffolds are valuable for constructing peptidomimetics, prodrugs, and pharmacophore libraries. The N-methyl group adds metabolic stability considerations relevant to drug design. Researchers in polymer chemistry may also find this compound useful as a monomer or crosslinker precursor.

Purity, Specifications, and Quality Assurance

Aladdin Scientific supplies 3,3'-(Methylimino)-dipropionic acid dimethyl ester under catalog number M694162. Researchers requiring specific purity grades, lot-specific Certificates of Analysis (CoA), or analytical data such as NMR, GC, or HPLC purity confirmation should contact Aladdin Scientific customer support or consult the product page directly.

When selecting a reagent grade for sensitive synthetic applications, confirm whether the supplied lot meets your required purity threshold. Aladdin Scientific can advise on available grades and packaging sizes to suit both discovery-scale and larger preparative needs.

Ordering and Procurement

To order 3,3'-(Methylimino)-dipropionic acid dimethyl ester, search for catalog number M694162 on the Aladdin Scientific website or contact your regional Aladdin representative. Bulk quantities, custom packaging, or specific purity grades may be available upon request — please reach out to the Aladdin Scientific sales team for a quotation.

For institutions requiring documentation such as Safety Data Sheets, Certificates of Analysis, or regulatory compliance information prior to purchase, these can be requested through the Aladdin Scientific customer service portal. Standard shipping conditions and payment options are detailed on the Aladdin Scientific ordering page.

Frequently asked questions

What is the molecular structure of 3,3'-(Methylimino)-dipropionic acid dimethyl ester?

The compound features a central tertiary amine nitrogen bearing a methyl group, with two propionic acid methyl ester chains (–CH2CH2COOCH3) attached to the nitrogen. This gives a symmetrical, bifunctional structure with one amine center and two ester groups.

How should I store 3,3'-(Methylimino)-dipropionic acid dimethyl ester to maintain its stability?

Store the compound in a tightly sealed container in a cool, dry location away from moisture, light, and strong bases. For extended storage, an inert atmosphere (nitrogen or argon) is recommended to prevent hydrolysis of the ester groups. Refer to the Aladdin Scientific SDS for the specific recommended storage temperature.

What are the typical synthetic applications of this compound?

3,3'-(Methylimino)-dipropionic acid dimethyl ester is used as a synthetic intermediate in organic and medicinal chemistry. Its ester groups can be hydrolyzed, amidated, or reduced, while the amine center can coordinate metal ions. Applications include the preparation of chelating ligands, peptidomimetic scaffolds, and pharmaceutical building blocks.

Where can I find the Certificate of Analysis (CoA) for catalog number M694162?

Lot-specific Certificates of Analysis for M694162 can be obtained through the Aladdin Scientific product page or by contacting Aladdin Scientific customer service with your lot number. CoAs typically include purity data and analytical characterization results.

Is 3,3'-(Methylimino)-dipropionic acid dimethyl ester available in bulk quantities?

Bulk quantities may be available upon request. Contact the Aladdin Scientific sales team directly with your quantity requirements to inquire about bulk pricing, lead times, and available packaging options for catalog number M694162.

References

1. Aladdin Scientific product page for 3,3'-(Methylimino)-dipropionic acid dimethyl ester, catalog number M694162.
2. General reference: March, J. Advanced Organic Chemistry: Reactions, Mechanisms, and Structure. Wiley, for ester reactivity and amino ester chemistry (textbook-level background).

Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.