Bicyclo[1.1.1]pentane, or BCP, is a rigid cage-like framework. The two bridgehead substituents in 1,3-disubstituted BCPs extend in directions approaching 180°, making this scaffold useful in studies involving three-dimensional bioisosteric replacement of para-disubstituted benzene rings. ...
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BCP
Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.
2 resources · protocols, FAQs & articles
The benzene ring can restrict molecular conformation, control substituent orientation, and participate in target binding through hydrophobic interactions, π–π interactions, or cation–π interactions. It is therefore widely present in drug molecules. However, in some lead compounds, ...
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Techniques often explored alongside immunological experiments.