The endoplasmic reticulum maintains protein homeostasis through molecular chaperones, endoplasmic reticulum-associated degradation, and endoplasmic reticulum-selective autophagy. Abnormal proteins that can be unfolded are mainly retrotranslocated through ERAD and degraded by the proteasome, ...
cell death
Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.
The PLSCR family is commonly used to study changes in membrane phospholipid asymmetry, phosphatidylserine (PS) externalization, cell death, platelet procoagulant activation, and inflammatory stress responses. In experiments, PLSCR expression changes, membrane localization changes, PS ...
The TWEAK-Fn14 pathway is a signaling axis within the TNF superfamily that integrates inflammatory regulation, tissue remodeling, and cell fate control.
Techniques often explored alongside immunological experiments.
