Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by disruption of immune tolerance, persistent exposure of nucleic acid autoantigens, autoantibody production, and immune-complex-mediated tissue injury. Its pathology is not driven by a single immune-cell ...
Topic
Complement
Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.
3 resources · protocols, FAQs & articles
In generalized myasthenia gravis (gMG), the therapeutic rationale for complement C5 inhibition is grounded in a well-defined immunopathological cascade.
Immunoglobulins are the central effector molecules of adaptive humoral immunity. They are produced by B cells and their terminally differentiated plasma cells and contribute to pathogen clearance, maintenance of immune homeostasis, and the development of immunopathology through a dual ...
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Techniques often explored alongside immunological experiments.