Neutrophils contain numerous effector proteins involved in host defense, including MPO, NE, Cathepsin G, PR3, BPI, Azurocidin, Lactoferrin, and Lysozyme. In human neutrophils, HNPs are also prominent α-defensin effectors. These proteins cooperate in pathogen clearance, whereas their persistent ...
Topic
defensins
Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.
2 resources · protocols, FAQs & articles
Defensins are cysteine-rich cationic antimicrobial peptides produced primarily by neutrophils, intestinal Paneth cells, and various mucosal epithelial cells. They can directly disrupt microbial membranes, entrap pathogens, recruit immune cells, and regulate the mucosal microbiota, making them ...
Related topics
Techniques often explored alongside immunological experiments.