In practice, however, the reaction involves two independent issues. First, the hydroxyl group itself is not a good leaving group, and the reactivity of the oxygen-containing functional group must therefore be modified before substitution can occur. Second, the nucleophilicity of fluoride is ...
Topic
Deoxyfluorination
Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.
2 resources · protocols, FAQs & articles
In their study Deoxyfluorination of Hydroxy-Substituted Boronates, published in ACS Organic & Inorganic Au, Melnyk and co-workers reported a deoxyfluorination method for hydroxyalkyl-substituted aryl/alkenyl boronates. This method converts an alcohol hydroxyl group into a C–F bond, namely a ...
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Techniques often explored alongside immunological experiments.