Drug development

Metabolic dysfunction-associated steatohepatitis is jointly driven by hepatic fat accumulation, lipotoxicity, insulin resistance, inflammation, and fibrosis. Targeting lipid metabolism, nuclear receptors, incretin pathways, and FGF signaling has become a major direction in drug development.

Animal modeling is an essential tool in biomedical research, designed to induce specific pathological, physiological, or genetic traits in experimental animals through particular experimental methods.

Aladdin® Target Proteins

The cytoskeleton is an essential scaffold within cells, composed of actin, tubulin, and intermediate filaments. It plays a crucial role in maintaining cell shape, cell movement, cell division, and signal transduction. Cytoskeletal staining reagents not only help researchers visualize the ...

Chelating agents, derived from the Greek word "chelate," meaning crab claws, vividly describe the ring-like complexes formed with metal ions. These complexes generally exhibit high stability in aqueous solutions and resist dissociation, though under specific conditions, metal ions can be ...

Peptide synthesis is a basic technique for peptide synthesis in biochemistry and molecular biology. It usually involves chemically linking amino acids in a specific order to create a desired peptide sequence.

The combination of stable isotope labeling with powerful mass spectrometric analytic techniques is providing increasingly important diagnostic tools for drug development and clinical diagnostics in the emerging era of personalized medicine.