Fibroblasts

Collagen is the principal structural protein of the dermal extracellular matrix (ECM). Intact collagen consists of three long polypeptide chains that form a triple helix and subsequently assemble into collagen fibrils and collagen fibers, providing the skin with tensile strength and mechanical ...

Platelet-derived growth factor (PDGF) is a class of disulfide-linked dimeric growth factors. It was originally named because it is present in platelet α-granules and is released after platelet activation. PDGF can promote the proliferation, migration, and chemotaxis of smooth muscle cells, ...