The gut microbiota can use dietary components, host secretions, and intrinsic microbial metabolic pathways to generate diverse classes of small-molecule compounds. These metabolites regulate the intestinal epithelial barrier, energy metabolism, immune-cell differentiation, and signaling in ...
immunotherapy
Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.
Nanobodies have the characteristics of small molecular size, high epitope accessibility, and flexible engineering potential, and can be used in tumor molecular imaging, targeted delivery, immune regulation, and engineered cell therapy.
Tumor immune killing depends not only on whether immune cells are present, but also on the balance between inhibitory and activating signals. NKG2A restricts NK cell and CD8⁺ T cell function through HLA-E, whereas NKG2D recognizes tumor stress ligands and enhances immune killing. Together, ...
Techniques often explored alongside immunological experiments.
