The side chain of proline connects back to the amino nitrogen to form a five-membered pyrrolidine ring, giving proline conformational characteristics distinct from those of most α-amino acids. Attaching a second carbocycle or heterocycle at the C3 position of proline produces a ...
Topic
molecular building block
Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.
2 resources · protocols, FAQs & articles
Lead compound optimization usually requires the simultaneous modulation of target activity, solubility, membrane permeability, metabolic stability, and nonspecific binding. A structural change may improve one property while shifting another outside the desired range. For example, basic amines ...
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Techniques often explored alongside immunological experiments.