Articles by tag "PKM2"

1. Regulation of Glycolytic Rate-Limiting Enzymes: Functional Comparison of Hexokinase, Phosphofructokinase, and Pyruvate Kinase
   posted this at 2026/07/27

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   Glycolytic rate-limiting enzymes determine the key nodes from glucose uptake and flux commitment to pyruvate formation. Hexokinase, phosphofructokinase, and pyruvate kinase respectively control early substrate trapping, irreversible mid-pathway flux commitment, and terminal ATP generation in ...
2. Research Progress on the Moonlighting Functions of Carbohydrate-Metabolic Enzymes in Replication Programs, DNA Damage Repair, and Inflammatory Activation
   posted this at 2026/04/14

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   The study of carbohydrate-metabolic enzymes has expanded beyond their classical catalytic roles to include higher-order cellular programs such as replication progression, DNA damage repair, and inflammatory activation. Multiple carbohydrate-metabolic enzymes can acquire moonlighting functions ...