Proteostasis

Aminopeptidases are a class of exopeptidases that act on the N-terminus of peptides and sequentially remove N-terminal amino acid residues. They participate in protein degradation, antigen peptide processing, peptide signal regulation, and disease development. The research focus is to analyze ...

Bacterial cytosol lacks the compartmentalized buffering characteristic of eukaryotic cells and instead constitutes a highly crowded, strongly interacting molecular environment. During co-translational and post-translational stages, nascent polypeptides experience prolonged exposure of ...