FH1 (BRD-K4477) - 10mM in DMSO , CAS No.2719-05-3

CAS: 2719-05-3 Cat. No.: F422957 分子式: C₁₇H₁₈N₂O₂ 分子量: 282.34 EC番号: 665-398-6

GRADE & PURITY 10mM in DMSO

Synonyms

N,N'-AcetylMDA | AC-33028 | N,N'-Diacetyl-4,4'-diaminodiphenylmethane | Paroil chlorez | Acetamide,N'-(methylenedi-4,1-phenylene)bis- | N,N'-(Methylenedi-4,1-phenylene)bis- acetamide | N-[4-[(4-acetamidophenyl)methyl]phenyl]acetamide | AM85691 | AKOS00281

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Information

FH1 (BRD-K4477) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.

In vitro

FH1(BRD-K4477) enhances hepatocyte functions, and promotes the maturation of well-differentiated cultures of iHeps, which potentially alleviates a major obstacle to the use of iPS cells as a renewable source of functional human hepatocytes.

Specifications

同義語

N,N'-AcetylMDA | AC-33028 | N,N'-Diacetyl-4,4'-diaminodiphenylmethane | Paroil chlorez | Acetamide,N'-(methylenedi-4,1-phenylene)bis- | N,N'-(Methylenedi-4,1-phenylene)bis- acetamide | N-[4-[(4-acetamidophenyl)methyl]phenyl]acetamide | AM85691 | AKOS00281

仕様と純度

10mM in DMSO

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

名前と識別子

• カノニカル・スマイル: CC(=O)NC1=CC=C(C=C1)CC2=CC=C(C=C2)NC(=O)C
• IUPAC Name: N-[4-[(4-acetamidophenyl)methyl]phenyl]acetamide
• InChIKey: OEXMNSOPAKOPEF-UHFFFAOYSA-N
• INCHI: 1S/C17H18N2O2/c1-12(20)18-16-7-3-14(4-8-16)11-15-5-9-17(10-6-15)19-13(2)21/h3-10H,11H2,1-2H3,(H,18,20)(H,19,21)
• 異性体SMILES: CC(=O)NC1=CC=C(C=C1)CC2=CC=C(C=C2)NC(=O)C
• 分子量: 282.34
• Reaxy-Rn: 2815695
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2815695&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • 分類 Benzene and substituted derivatives
      • Subclass Diphenylmethanes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• 分類: Benzene and substituted derivatives
• Subclass: Diphenylmethanes
• Intermediate Tree Nodes: Not available
• Direct Parent: Diphenylmethanes
• Alternative Parents: Acetanilides N-acetylarylamines Acetamides Secondary carboxylic acid amides Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Diphenylmethane - Acetanilide - N-acetylarylamine - Anilide - N-arylamide - Acetamide - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic nitrogen compound - Organic oxygen compound - Carbonyl group - Hydrocarbon derivative - Aromatic homomonocyclic compound
• 説明: This compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

関連ターゲット（非人間）

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用メカニズム

化学的性質と物理的性質

• 分子量: 282.340 g/mol
• XLogP3: 2.500
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 282.137 Da
• Monoisotopic Mass: 282.137 Da
• Topological Polar Surface Area: 58.200 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 320.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

よくある質問

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2719-05-3, the molecular formula is C17H18N2O2, and the molecular weight is 282.34 g/mol. InChIKey OEXMNSOPAKOPEF-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.