FlAsH-EDT2 - ≥95% , CAS No.212118-77-9

CAS: 212118-77-9 Cat. No.: F332805 分子式: C₂₄H₁₈As₂O₅S₄ 分子量: 664.5

GRADE & PURITY ≥95%

Synonyms

UNII-Z8CH38Y9L3 | 4',5'-bis(1,3,2-dithioarsolan-2-yl)fluorescein | FLASH-EDT2 | FlAsH-EDT-2 | SCHEMBL2266085 | DTXSID90431400 | J-013919 | 4',5'-bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one | FlAsH EDT2 | FT-0668535

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

概要

FlAsH-EDT2 is a fluorescence probe for labeling proteins. The Fluorescein Arsenical Hairpin Binder (FlAsH) method is presented for fluorescence labeling of proteins in living cells. Labeling proteins with the membrane-permeant fluorogenic biarsenical dye fluorescein arsenical hairpin binder-ethanedithiol (FlAsH-EDT2). The membrane-permeant fluorogenic biarsenicals FlAsH-EDT2 and ReAsH-EDT2 can be prepared in good yields by a straightforward two-step procedure from the inexpensive precursor dyes fluorescein and resorufin. FlAsH-EDT2 binds covalently to a tetracysteine sequence (CCPGCC).

Specifications

同義語

UNII-Z8CH38Y9L3 | 4',5'-bis(1,3,2-dithioarsolan-2-yl)fluorescein | FLASH-EDT2 | FlAsH-EDT-2 | SCHEMBL2266085 | DTXSID90431400 | J-013919 | 4',5'-bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one | FlAsH EDT2 | FT-0668535

仕様と純度

≥95%

保管条件

Protected from light,Store at -20°C,Argon charged

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

純度

≥95%

製品の性質

• 励起および放出範囲: λex 508 nm,λem 528 nm

名前と識別子

• パブケム・シド: 488196337
• パブケム・シド・ウル: https://pubchem.ncbi.nlm.nih.gov/substance/488196337
• カノニカル・スマイル: C1CS[As](S1)C2=C(C=CC3=C2OC4=C(C35C6=CC=CC=C6C(=O)O5)C=CC(=C4[As]7SCCS7)O)O
• IUPAC Name: 4',5'-bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
• InChIKey: AJNUQUGWNQHQDJ-UHFFFAOYSA-N
• INCHI: 1S/C24H18As2O5S4/c27-17-7-5-15-21(19(17)25-32-9-10-33-25)30-22-16(6-8-18(28)20(22)26-34-11-12-35-26)24(15)14-4-2-1-3-13(14)23(29)31-24/h1-8,27-28H,9-12H2
• 異性体SMILES: C1CS[As](S1)C2=C(C=CC3=C2OC4=C(C35C6=CC=CC=C6C(=O)O5)C=CC(=C4[As]7SCCS7)O)O
• 分子量: 664.5
• Reaxy-Rn: 10621881
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=10621881&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 分類 Benzopyrans
      • Subclass 1-benzopyrans
        • Level5 Dibenzopyrans
          • Level6 Xanthenes

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 分類: Benzopyrans
• Subclass: 1-benzopyrans
• Intermediate Tree Nodes: Dibenzopyrans
• Direct Parent: Xanthenes
• Alternative Parents: Diarylethers Phthalides Benzofuranones Isobenzofurans 1-hydroxy-2-unsubstituted benzenoids Trivalent organic arsenic compounds Lactones Carboxylic acid esters Oxygen-containing organoarsenic compounds Oxacyclic compounds Organoarsenic sulfides Organic metalloid salts Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Xanthene - Diaryl ether - Benzofuranone - Isobenzofuranone - Phthalide - Isocoumaran - Isobenzofuran - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Benzenoid - Carboxylic acid ester - Lactone - Trivalent organic arsenic compound - Sulfur-containing organoarsenic compound - Organoarsenic sulfide - Oxygen-containing organoarsenic compound - Ether - Organic metalloid salt - Carboxylic acid derivative - Oxacycle - Hydrocarbon derivative - Organooxygen compound - Organoarsenic compound - Organic metalloid moeity - Organic oxygen compound - Organic oxide - Aromatic heteropolycyclic compound
• 説明: This compound belongs to the class of organic compounds known as xanthenes. These are polycyclic aromatic compounds containing a xanthene moiety, which consists of two benzene rings joined to each other by a pyran ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

化学的性質と物理的性質

• 溶解度: Soluble in chloroform.
• 感度: light sensitive；Moisture sensitive
• 沸点（°C）: 849.8° C at 760 mmHg (Predicted)
• 融点（°C）: 169-172° C (dec.)
• 分子量: 664.500 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 2
• Exact Mass: 663.847 Da
• Monoisotopic Mass: 663.847 Da
• Topological Polar Surface Area: 177.000 Ų
• Heavy Atom Count: 35
• Formal Charge: 0
• Complexity: 784.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

XLogP3