Gallamine Triethiodide - Moligand™, 10mM in DMSO , Muscle-type nicotinic acetylcholine receptor antagonist, CAS No.65-29-2, Muscle-type nicotinic acetylcholine receptor antagonist

CAS: 65-29-2 Cat. No.: G408368 分子式: C₃₀H₆₀I₃N₃O₃ 分子量: 891.53 EC番号: 200-605-1 PubChem CID: 6172

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

2,​2',​2''-​[1,​2,​3-​benzenetriyltris(oxy​)​]​tris[N,​N,​N-​triethyl-ethanaminium, iodide (1:3)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Information

Gallamine Triethiodide Gallamine Triethiodide is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥97%

Specifications

同義語

2,​2',​2''-​[1,​2,​3-​benzenetriyltris(oxy​)​]​tris[N,​N,​N-​triethyl-ethanaminium, iodide (1:3)

仕様と純度

Moligand™, 10mM in DMSO

生化学的・生理学的メカニズム

Gallamine Triethiodide is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

ALLOSTERIC MODULATOR, ANTAGONIST, CHANNEL BLOCKER

作用メカニズム

Muscle-type nicotinic acetylcholine receptor antagonist

名前と識別子

• 異性体SMILES: CC[N+](CC)(CC)CCOC1=C(C(=CC=C1)OCC[N+](CC)(CC)CC)OCC[N+](CC)(CC)CC.[I-].[I-].[I-]
• WGKドイツ: 3
• RTECS: BS1100000
• PubChem CID: 6172
• 分子量: 891.53

関連ターゲット（人間）

CHRNA1 Tclin Acetylcholine receptor subunit alpha (1 Activities)

Discover Target: CHRNA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM2 Tclin Muscarinic acetylcholine receptor M2 (1 Activities)

Discover Target: CHRM2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

化学的性質と物理的性質

• 融点（°C）: 235 °C

参考文献

1. Lin Huang, Weixia Zhang, Difei Tong, Lingzheng Lu, Weishang Zhou, Dandan Tian, Guangxu Liu, Wei Shi.  (2023)  Triclosan and triclocarban weaken the olfactory capacity of goldfish by constraining odorant recognition, disrupting olfactory signal transduction, and disturbing olfactory information processing.  WATER RESEARCH,      [PMID:36801581] [10.1016/j.watres.2023.119736]

2. Petrus Siregar, Gilbert Audira, Ling-Yi Feng, Jia-Hau Lee, Fiorency Santoso, Wen-Hao Yu, Yu-Heng Lai, Jih-Heng Li, Ying-Ting Lin, Jung-Ren Chen, Chung-Der Hsiao.  (2021)  Pharmaceutical Assessment Suggests Locomotion Hyperactivity in Zebrafish Triggered by Arecoline Might Be Associated with Multiple Muscarinic Acetylcholine Receptors Activation.  Toxins,  13  (4): (259).  [PMID:33916832] [10.3390/toxins13040259]

よくある質問

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 65-29-2, the molecular formula is C30H60I3N3O3, and the molecular weight is 891.53 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.