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GK921 - ≥98% , CAS No.1025015-40-0

CAS: 1025015-40-0 Cat. No.: G413442 分子式: C21H20N4O 分子量: 344.41
COA
GK921 - ≥98% CAS No(1025015-40-0) by Aladdin Scientific
注文可能
GRADE & PURITY ≥98%
Synonyms
Pyrido[2,​3-​b]​pyrazine,3-​(2-​phenylethynyl)​-​2-​[2-​(1-​pyrrolidinyl)​ethoxy]​- | 3-(2-Phenylethynyl)-2-[2-(1-pyrrolidinyl)ethoxy]pyrido[2,3-b]pyrazine, 3-(Phenylethynyl)-2-(2-(pyrrolidin-1-yl)ethoxy)pyrido[3,2-b]pyrazine, GK 921, GK-921
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
USA
ドイツ (EU)*
Price
Qty
1mg
G413442-1mg
受注生産 · 8～12週間
$64.90
2mg
G413442-2mg
3 在庫あり
—
$165.90
5mg
G413442-5mg
1 在庫あり
—
$231.90
10mg
G413442-10mg
1 在庫あり
—
$287.90
25mg
G413442-25mg
1 在庫あり
—
$387.90
50mg
G413442-50mg
1 在庫あり
—
$635.90
100mg
G413442-100mg
1 在庫あり
—
$1,081.90
200mg
G413442-200mg
受注生産 · 8～12週間
$1,690.90
Enter a quantity for the sizes you want to add.
Bulk / Custom
♡ ウィッシュリスト ⇅ 比較リストに入れる ⎙ Print page
SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Specifications 製品の性質 名前と識別子 Documentation Advanced Data Taxonomic Classification 3 D構造 関連ターゲット（人間） 関連ターゲット（非人間） 作用メカニズム 証明書（CoA、COO、BSE/TSEと分析図） 化学的性質と物理的性質 ソリューション計算機 レビュー
🧪
Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

同義語
Pyrido[2,​3-​b]​pyrazine,3-​(2-​phenylethynyl)​-​2-​[2-​(1-​pyrrolidinyl)​ethoxy]​- | 3-(2-Phenylethynyl)-2-[2-(1-pyrrolidinyl)ethoxy]pyrido[2,3-b]pyrazine, 3-(Phenylethynyl)-2-(2-(pyrrolidin-1-yl)ethoxy)pyrido[3,2-b]pyrazine, GK 921, GK-921
仕様と純度
≥98%
生化学的・生理学的メカニズム
GK921 is a transglutaminase 2 (TGase 2) inhibitor with an IC50 of 8.93 μM under a modified assay condition.GK921 is an orally active transglutaminase 2 (TG2, TGase 2) inhibitor (IC50 = 7.71 μM) that effectively inhibits TG2-mediated I-κBα and p53 polymeri
保管条件
Store at -20°C
入荷
Ice chest + Ice pads
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
アクションタイプ
INHIBITOR
純度
≥98%
製品の性質
ALogP
3.998
hba_count
4
回転可能な結合
6
名前と識別子
パブケム・シド
488201742
パブケム・シド・ウル
https://pubchem.ncbi.nlm.nih.gov/substance/488201742
カノニカル・スマイル
C1CCN(C1)CCOC2=NC3=C(N=CC=C3)N=C2C#CC4=CC=CC=C4
IUPAC Name
3-(2-phenylethynyl)-2-(2-pyrrolidin-1-ylethoxy)pyrido[2,3-b]pyrazine
InChIKey
MNYJJHBAEYKXEG-UHFFFAOYSA-N
INCHI
1S/C21H20N4O/c1-2-7-17(8-3-1)10-11-19-21(26-16-15-25-13-4-5-14-25)24-18-9-6-12-22-20(18)23-19/h1-3,6-9,12H,4-5,13-16H2
異性体SMILES
C1CCN(C1)CCOC2=NC3=C(N=CC=C3)N=C2C#CC4=CC=CC=C4
分子量
344.41
Reaxy-Rn
21826827
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=21826827&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
分類Pyridopyrazines
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentPyridopyrazines
Alternative Parents Alkyl aryl ethers  Pyridines and derivatives  Pyrazines  N-alkylpyrrolidines  Benzene and substituted derivatives  Heteroaromatic compounds  Trialkylamines  Azacyclic compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Pyridopyrazine - Alkyl aryl ether - Monocyclic benzene moiety - Pyrazine - Pyridine - Benzenoid - N-alkylpyrrolidine - Heteroaromatic compound - Pyrrolidine - Tertiary aliphatic amine - Tertiary amine - Azacycle - Ether - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Amine - Aromatic heteropolycyclic compound
説明This compound belongs to the class of organic compounds known as pyridopyrazines. These are aromatic heteropolycyclic compounds containing a pyridine ring fused to a pyrazine ring.
External Descriptors Not available
3 D構造
インタラクティブ化学構造モデル





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関連ターゲット（非人間）
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作用メカニズム
証明書（CoA、COO、BSE/TSEと分析図）
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

13 results found

Lot NumberCertificate Type日付商品
C23231461Certificate of AnalysisJan 19, 2026 G413442
C23231455Certificate of AnalysisDec 16, 2022 G413442
C23231459Certificate of AnalysisDec 16, 2022 G413442
C23231460Certificate of AnalysisDec 16, 2022 G413442
C23231462Certificate of AnalysisDec 16, 2022 G413442
C23231463Certificate of AnalysisDec 16, 2022 G413442
C23231464Certificate of AnalysisDec 16, 2022 G413442
C23231465Certificate of AnalysisDec 16, 2022 G413442
C23231466Certificate of AnalysisDec 16, 2022 G413442
C23231467Certificate of AnalysisDec 16, 2022 G413442
C2324003Certificate of AnalysisDec 16, 2022 G413442
C2324004Certificate of AnalysisDec 16, 2022 G413442
C2324009Certificate of AnalysisDec 16, 2022 G413442
化学的性質と物理的性質
溶解度Solubility (25°C) In vitro DMSO: 33 mg/mL (95.81 mM);    
DMSO（mg / mL） 最大溶解度33
DMSO（mM） 最大溶解度95.8160332162248
水（mg / mL） 最大溶解度-1
分子量344.400 g/mol
XLogP33.400
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass344.164 Da
Monoisotopic Mass344.164 Da
Topological Polar Surface Area51.100 Ų
Heavy Atom Count26
Formal Charge0
Complexity501.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
ソリューション計算機
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