Hemorphin-7 , CAS No.152685-85-3

CAS: 152685-85-3 Cat. No.: H651525 分子式: C₄₉H₆₄N₁₂O₁₁ 分子量: 997.11 PubChem CID: 132952

Synonyms

PD100078 | HY-P0318 | L-tyrosyl-L-prolyl-L-tryptophyl-L-threonyl-L-glutaminyl-L-arginyl-L-phenylalanine | L-Phenylalanine, N-(N2-(N2-(N-(N-(1-L-tyrosyl-L-prolyl)-L-tryptophyl)-L-threonyl)-L-glutaminyl)-L-arginyl)- | Tyr-pro-trp-thr-gln-arg-phe | Hemorphin

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Hemorphin-7 is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin peptides exhibits antinociceptive and antihypertensive activities, activating opioid receptors and inhibiting angiotensin-converting enzyme (ACE) .

Form:Solid

Specifications

同義語

PD100078 | HY-P0318 | L-tyrosyl-L-prolyl-L-tryptophyl-L-threonyl-L-glutaminyl-L-arginyl-L-phenylalanine | L-Phenylalanine, N-(N2-(N2-(N-(N-(1-L-tyrosyl-L-prolyl)-L-tryptophyl)-L-threonyl)-L-glutaminyl)-L-arginyl)- | Tyr-pro-trp-thr-gln-arg-phe | Hemorphin

生化学的・生理学的メカニズム

Hemorphin-7 is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin peptides exhibits antinociceptive and antihypertensive activities, activating opioid receptors and inhibiting angiotensin-converting enzyme

保管条件

Desiccated,Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

ACTIVATOR

名前と識別子

カノニカル・スマイル

CC(C(C(=O)NC(CCC(=O)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC1=CC=CC=C1)C(=O)O)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C4CCCN4C(=O)C(CC5=CC=C(C=C5)O)N)O

IUPAC Name

(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxybutanoyl]amino]-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoic acid

InChIKey

PAJVBIPSWDYNHN-JMJBHNTOSA-N

INCHI

1S/C49H64N12O11/c1-27(62)41(46(69)57-36(19-20-40(51)64)43(66)56-35(13-7-21-54-49(52)53)42(65)59-38(48(71)72)24-28-9-3-2-4-10-28)60-44(67)37(25-30-26-55-34-12-6-5-11-32(30)34)58-45(68)39-14-8-22-61(39)47(70)33(50)23-29-15-17-31(63)18-16-29/h2-6,9-12,15-18,26-27,33,35-39,41,55,62-63H,7-8,13-14,19-25,50H2,1H3,(H2,51,64)(H,56,66)(H,57,69)(H,58,68)(H,59,65)(H,60,67)(H,71,72)(H4,52,53,54)/t27-,33+,35+,36+,37+,38+,39+,41+/m1/s1

異性体SMILES

C[C@H]([C@@H](C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CC5=CC=C(C=C5)O)N)O

代替CAS番号

152685-85-3

PubChem CID

132952

MeSH用語

hemorphin 7;hemorphin-7;Tyr-Pro-Trp-Thr-Gln-Arg-Phe;tyrosyl-prolyl-tryptophyl-threonyl-glutaminyl-arginyl-phenylalanine

分子量

997.11

化学的性質と物理的性質

• 溶解度: H2O : 12.5 mg/mL (12.54 mM; Need ultrasonic)
• 分子量: 997.100 g/mol
• XLogP3: -3.000
• Hydrogen Bond Donor Count: 13
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 26
• Exact Mass: 996.482 Da
• Monoisotopic Mass: 996.482 Da
• Topological Polar Surface Area: 393.000 Ų
• Heavy Atom Count: 72
• Formal Charge: 0
• Complexity: 1890.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 8
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1