Hexamethonium Chloride hydrate - ≥99% , CAS No.60-25-3(anhy)

CAS: 60-25-3(anhy) Cat. No.: H157034 分子式: C₁₂H₃₀Cl₂N₂·xH₂O 分子量: 273.29(anhy)

GRADE & PURITY ≥99%

Synonyms

Hexamethylenebis(trimethylammonium Chloride) hydrate | N,N,N,N',N',N'-Hexamethyl-1,6-hexanediammonium Dichloride hydrate | Hexane-1,6-bis(trimethylammonium Chloride) hydrate

Storage

Argon charged,Room temperature

Shipped In

Normal

概要

Nicotinic acetylcholine receptor (nAChR) forms a ligand-gated ion channel made up of four different subunits. Each subunit contains an extracellular amino-terminal domain (hydrophilic) and carboxylic terminal domain and four transmembrane domains. nAChR is an allosteric and transmembrane protein localized to the neuromuscular junction. 

Application：

Hexamethonium chloride has been used to block the responses of nicotinic receptors towards it agonists. It has also been used to study the mechanosensitivity of viscerofugal neurons.

Specifications

同義語

Hexamethylenebis(trimethylammonium Chloride) hydrate | N,N,N,N',N',N'-Hexamethyl-1,6-hexanediammonium Dichloride hydrate | Hexane-1,6-bis(trimethylammonium Chloride) hydrate

仕様と純度

≥99%

生化学的・生理学的メカニズム

Hexamethonium chloride preferentially blocks nicotinic receptors at autonomic ganglia,crosses blood-brain barrier only at high doses. Nicotinic acetylcholine receptor (nAChR) is responsible for cognitive functions. Blocking this receptor results in cognit

保管条件

Argon charged,Room temperature

入荷

Normal

純度

≥99%

名前と識別子

• 代替CAS番号: 16986-49-5
• 分子量: 273.29(anhy)

化学的性質と物理的性質

• 溶解度: Soluble in water; Soluble in Ethanol; Insoluble in Ether,Chloroform
• 感度: Hygroscopic

よくある質問

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at room temperature under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships under standard ambient conditions. No temperature-controlled packaging is required.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 60-25-3(anhy), the molecular formula is C12H30Cl2N2·xH2O, and the molecular weight is 273.29(anhy) g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.