Hispidol - ≥98% , CAS No.5786-54-9

CAS: 5786-54-9 Cat. No.: H412270 分子式: C15H10O4 分子量: 254.24
注文可能
GRADE & PURITY ≥98%
Synonyms
(2Z)-6-hydroxy-2-[(4-hydroxyphenyl)methylidene]-1-benzofuran-3-one | (Z)-Hispidol | CS1235I0WT | 3(2H)-Benzofuranone, 6-hydroxy-2-((4-hydroxyphenyl)methylene)-, (2Z)- | Hispidol | NSC356828 | NSC-356828 | (2Z)-6-hydroxy-2-[(4-hydroxyphenyl)methylidene]-1-
Storage
Store at 2-8°C
Shipped In
Wet ice
★
Size
USA
ドイツ (EU)*
Price
Qty
1mg
H412270-1mg
受注生産 · 8~12週間
$49.90
5mg
H412270-5mg
3 在庫あり
—

$176.90

$265.90
保存 $89.00 (33.47%)
10mg
H412270-10mg
3 在庫あり
—

$320.90

$481.90
保存 $161.00 (33.41%)
25mg
H412270-25mg
2 在庫あり
—

$628.90

$943.90
保存 $315.00 (33.37%)
50mg
H412270-50mg
1 在庫あり
—

$1,070.90

$1,606.90
保存 $536.00 (33.36%)
100mg
H412270-100mg
1 在庫あり
—

$1,927.90

$2,891.90
保存 $964.00 (33.33%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

概要

Information

Hispidol ((Z)-Hispidol) is an inhibitor of TNF-α induced adhesion of monocytes to colon epithelial cells with IC50 of 0.50 µM. Hispidol is a potential therapeutic for inflammatory bowel disease.

Specifications

同義語
(2Z)-6-hydroxy-2-[(4-hydroxyphenyl)methylidene]-1-benzofuran-3-one | (Z)-Hispidol | CS1235I0WT | 3(2H)-Benzofuranone, 6-hydroxy-2-((4-hydroxyphenyl)methylene)-, (2Z)- | Hispidol | NSC356828 | NSC-356828 | (2Z)-6-hydroxy-2-[(4-hydroxyphenyl)methylidene]-1-
仕様と純度
≥98%
生化学的・生理学的メカニズム
Hispidol ((Z)-Hispidol) is an inhibitor of TNF-α induced adhesion of monocytes to colon epithelial cells with IC50 of 0.50 µM. Hispidol is a potential therapeutic for inflammatory bowel disease.
保管条件
Store at 2-8°C
入荷
Wet ice
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
アクションタイプ
INHIBITOR
純度
≥98%
名前と識別子
パブケム・シド508810580
カノニカル・スマイルC1=CC(=CC=C1C=C2C(=O)C3=C(O2)C=C(C=C3)O)O
IUPAC Name(2Z)-6-hydroxy-2-[(4-hydroxyphenyl)methylidene]-1-benzofuran-3-one
InChIKeyKEZLDSPIRVZOKZ-AUWJEWJLSA-N
INCHI1S/C15H10O4/c16-10-3-1-9(2-4-10)7-14-15(18)12-6-5-11(17)8-13(12)19-14/h1-8,16-17H/b14-7-
異性体SMILES C1=CC(=CC=C1/C=C\2/C(=O)C3=C(O2)C=C(C=C3)O)O
分子量 254.24
Reaxy-Rn 22564380
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=22564380&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassPhenylpropanoids and polyketides
分類Aurone flavonoids
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentAurone flavonoids
Alternative Parents Coumarans  Benzofurans  Aryl ketones  1-hydroxy-2-unsubstituted benzenoids  Benzene and substituted derivatives  Oxacyclic compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Aurone - Benzofuran - Coumaran - Aryl ketone - Phenol - 1-hydroxy-2-unsubstituted benzenoid - Benzenoid - Monocyclic benzene moiety - Ketone - Oxacycle - Organoheterocyclic compound - Hydrocarbon derivative - Organooxygen compound - Organic oxygen compound - Organic oxide - Aromatic heteropolycyclic compound
説明This compound belongs to the class of organic compounds known as aurone flavonoids. These are flavonoids containing a 2-Benzylidene-1-benzofuran-3-one based core. Aurone flavonoids provide the bright yellow color of some important ornamental flowers, such as snapdragon (Antirrhinum majus).
External Descriptors aurones - Aurone flavonoids
3 D構造
インタラクティブ化学構造モデル





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Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
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Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
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MAOB Tclin Monoamine oxidase B (8835 Activities)
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ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
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ADORA2A Tclin Adenosine A2a receptor (16305 Activities)
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作用メカニズム
証明書(CoA、COO、BSE/TSEと分析図)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate Type日付商品
B2423478Certificate of AnalysisJan 12, 2024 H412270
B2423482Certificate of AnalysisJan 12, 2024 H412270
B2423483Certificate of AnalysisJan 12, 2024 H412270
B2423484Certificate of AnalysisJan 12, 2024 H412270
B2423485Certificate of AnalysisJan 12, 2024 H412270
B2423486Certificate of AnalysisJan 12, 2024 H412270
B2423493Certificate of AnalysisJan 12, 2024 H412270
B2423494Certificate of AnalysisJan 12, 2024 H412270
B2423495Certificate of AnalysisJan 12, 2024 H412270
B2423496Certificate of AnalysisJan 12, 2024 H412270
化学的性質と物理的性質
分子量254.240 g/mol
XLogP32.900
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass254.058 Da
Monoisotopic Mass254.058 Da
Topological Polar Surface Area66.800 Ų
Heavy Atom Count19
Formal Charge0
Complexity382.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
ソリューション計算機
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