IMR-1A - ≥97% , CAS No.331862-41-0

CAS: 331862-41-0 Cat. No.: I412257 分子式: C₁₃H₁₁NO₅S₂ 分子量: 325.36

GRADE & PURITY ≥97%

Synonyms

Acetic acid,2-​[2-​methoxy-​4-​[(4-​oxo-​2-​thioxo-​5-​thiazolidinylidene)​methyl]​phenoxy]​-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

概要

Information

IMR-1A IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.

Targets

Notch (Cell-free assay); Notch (Cell-free assay) 0.5 μM; 2.9 μM(Kd)

Specifications

同義語

Acetic acid,2-​[2-​methoxy-​4-​[(4-​oxo-​2-​thioxo-​5-​thiazolidinylidene)​methyl]​phenoxy]​-

仕様と純度

≥97%

生化学的・生理学的メカニズム

IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

純度

≥97%

製品の性質

• ALogP: 2.29
• hba_count: 4
• HBD数: 1
• 回転可能な結合: 5

名前と識別子

• パブケム・シド: 488191798
• パブケム・シド・ウル: https://pubchem.ncbi.nlm.nih.gov/substance/488191798
• カノニカル・スマイル: COC1=C(C=CC(=C1)C=C2C(=O)NC(=S)S2)OCC(=O)O
• IUPAC Name: 2-[2-methoxy-4-[(E)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid
• InChIKey: DVBJNSKWHSGTDK-BJMVGYQFSA-N
• INCHI: 1S/C13H11NO5S2/c1-18-9-4-7(2-3-8(9)19-6-11(15)16)5-10-12(17)14-13(20)21-10/h2-5H,6H2,1H3,(H,15,16)(H,14,17,20)/b10-5+
• 分子量: 325.36
• Reaxy-Rn: 29764446
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29764446&ln=

化学的性質と物理的性質

• 溶解度: Solubility (25°C) In vitro DMSO: 6 mg/mL (18.44 mM); Water: Insoluble; Ethanol: Insoluble
• DMSO（mg / mL） 最大溶解度: 6
• DMSO（mM） 最大溶解度: 18.4411113843128
• 水（mg / mL） 最大溶解度: ＜1

よくある質問

What is the purity of this product?

This product is supplied at ≥97% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 331862-41-0, the molecular formula is C13H11NO5S2, and the molecular weight is 325.36 g/mol. InChIKey DVBJNSKWHSGTDK-BJMVGYQFSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.