INDY - ≥98% , CAS No.1169755-45-6

CAS: 1169755-45-6 Cat. No.: I275280 分子式: C₁₂H₁₃NO₂S 分子量: 235.3

GRADE & PURITY ≥98%

Synonyms

(1Z)-1-(3-Ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone | (Z)-1-(3-ethyl-5-hydroxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

概要

Shipped at Room Temperature. Store at +4°C short term (1-2 weeks). Store at -20°C.

Specifications

同義語

(1Z)-1-(3-Ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone | (Z)-1-(3-ethyl-5-hydroxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one

仕様と純度

≥98%

生化学的・生理学的メカニズム

Potent DYRK1A/B inhibitor (IC 50 values are 0.23 and 0.24\xa0µM for DYRK1B and DYRK1A respectively). Also inhibits DYRK2, DTRK4, CLK1, CLK4, casein kinase 1 and PIM1 (> 90% inhibition at 10 μM).

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

INHIBITOR

注

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

純度

≥98%

名前と識別子

• パブケム・シド: 488202143
• パブケム・シド・ウル: https://pubchem.ncbi.nlm.nih.gov/substance/488202143
• カノニカル・スマイル: CCN1C2=C(C=CC(=C2)O)SC1=CC(=O)C
• IUPAC Name: 1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2-ylidene)propan-2-one
• InChIKey: GCSZJMUFYOAHFY-UHFFFAOYSA-N
• INCHI: 1S/C12H13NO2S/c1-3-13-10-7-9(15)4-5-11(10)16-12(13)6-8(2)14/h4-7,15H,3H2,1-2H3
• 異性体SMILES: CCN1C2=C(C=CC(=C2)O)SC1=CC(=O)C
• 分子量: 235.3
• Reaxy-Rn: 28418243
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=28418243&ln=

化学的性質と物理的性質

• 溶解度: Soluble in DMSO to 100 mM