IQDMA - ≥98% , CAS No.401463-02-3

CAS: 401463-02-3 Cat. No.: I275346 分子式: C₁₉H₂₀N₄ 分子量: 304.39

グレード＆純度 ≥98%

Synonyms

N2-11H-Indolo[3,2-c]quinolin-6-yl-N1,N1-dimethyl-1,2-ethanediamine

Storage

Store at 2-8°C

Shipped In

Wet ice

概要

Store at +4°C. The product can be stored for up to 12 months.

仕様

同義語

N2-11H-Indolo[3,2-c]quinolin-6-yl-N1,N1-dimethyl-1,2-ethanediamine

仕様と純度

≥98%

生化学的・生理学的メカニズム

Cell-permeable STAT5 inhibitor (IC 50 = 8 μM). Indoloquinoline derivative. Antineoplastic agent with broad spectrum antitumor activity seen in vitro . Induces cell-cycle arrest at the G 2 /M phase.

保管条件

Store at 2-8°C

入荷

Wet ice

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

注

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

純度

≥98%

名前と識別子

カノニカル・スマイル

CN(C)CCNC1=NC2=CC=CC=C2C3=C1C4=CC=CC=C4N3

IUPAC Name

N-(11H-indolo[3,2-c]quinolin-6-yl)-N',N'-dimethylethane-1,2-diamine

InChIKey

UROLFQZUYMCOHV-UHFFFAOYSA-N

INCHI

1S/C19H20N4/c1-23(2)12-11-20-19-17-13-7-3-5-9-15(13)21-18(17)14-8-4-6-10-16(14)22-19/h3-10,21H,11-12H2,1-2H3,(H,20,22)

異性体SMILES

CN(C)CCNC1=NC2=CC=CC=C2C3=C1C4=CC=CC=C4N3

分子量

304.39

Reaxy-Rn

20206145

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20206145&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 分類 Quinolines and derivatives
      • Subclass Indoloquinolines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 分類: Quinolines and derivatives
• Subclass: Indoloquinolines
• Intermediate Tree Nodes: Not available
• Direct Parent: Indoloquinolines
• Alternative Parents: Pyrrolo[3,2-c]quinolines Gamma carbolines Aminoquinolines and derivatives Pyrrolopyridines Indoles Aminopyridines and derivatives Imidolactams Benzenoids Pyrroles Heteroaromatic compounds Trialkylamines Azacyclic compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Indoloquinoline - Pyrrolo[3,2-c]quinoline - Gamma-carboline - Pyrroloquinoline - Aminoquinoline - Indole - Indole or derivatives - Pyrrolopyridine - Aminopyridine - Pyridine - Benzenoid - Imidolactam - Pyrrole - Heteroaromatic compound - Tertiary amine - Tertiary aliphatic amine - Azacycle - Organic nitrogen compound - Organonitrogen compound - Amine - Hydrocarbon derivative - Aromatic heteropolycyclic compound
• 説明: This compound belongs to the class of organic compounds known as indoloquinolines. These are polycyclic aromatic compounds containing an indole fused to a quinoline.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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関連ターゲット（非人間）

Plasmodium falciparum (966862 Activities)

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作用メカニズム

化学的性質と物理的性質

• 溶解度: Soluble in DMSO to 100 mM and in ethanol to 100 mM

よくある質問

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 401463-02-3, the molecular formula is C19H20N4, and the molecular weight is 304.39 g/mol. InChIKey UROLFQZUYMCOHV-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.