(±)-J 113397 - ≥98% , CAS No.217461-40-0

CAS: 217461-40-0 Cat. No.: J287289 分子式: C₂₄H₃₇N₃O₂ 分子量: 399.57 PubChem CID: 90488772

GRADE & PURITY ≥98%

Synonyms

(±)-1-[(3R*,4R*)-1-(Cyclooctylmethyl)-3-(hydroxymethyl)-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one

Storage

Protected from light,Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Specifications

同義語

(±)-1-[(3R*,4R*)-1-(Cyclooctylmethyl)-3-(hydroxymethyl)-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one

仕様と純度

≥98%

生化学的・生理学的メカニズム

(±) - J-113397 is an effective and selective non peptide ORL1 receptor antagonist with a Ki of 1.8 nM against human cloned ORL1. J-113397 inhibits the binding of GTP γ S stimulated by nociceptin/orphan FQ to CHO cells expressing ORL1, with an IC50 value o

保管条件

Protected from light,Store at -20°C,Desiccated

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

ANTAGONIST

純度

≥98%

名前と識別子

カノニカル・スマイル

CCN1C4=C(C=CC=C4)N([C@@H]2CCN(CC3CCCCCCC3)C[C@H]2CO)C1=O.CCN5C8=C(C=CC=C8)N([C@H]6CCN(CC7CCCCCCC7)C[C@@H]6CO)C5=O

InChIKey

NLSVMRCGZVSAFK-SDNSQTLOSA-N

異性体SMILES

CCN1C2=CC=CC=C2N(C1=O)[C@@H]3CCN(C[C@H]3CO)CC4CCCCCCC4.CCN1C2=CC=CC=C2N(C1=O)[C@H]3CCN(C[C@@H]3CO)CC4CCCCCCC4

PubChem CID

90488772

分子量

399.57

化学的性質と物理的性質

• 溶解度: Solvent:DMSO, Max Conc. mg/mL: 19.98, Max Conc. mM: 50; Solvent:ethanol, Max Conc. mg/mL: 19.98, Max Conc. mM: 50
• 感度: Light and Moisture sensitive

よくある質問

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, protected from light, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 217461-40-0, the molecular formula is C24H37N3O2, and the molecular weight is 399.57 g/mol. InChIKey NLSVMRCGZVSAFK-SDNSQTLOSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.