L-Anserine - 10mM in Water , CAS No.584-85-0

CAS: 584-85-0 Cat. No.: L424892 分子式: C₁₀H₁₆N₄O₃ 分子量: 240.26

GRADE & PURITY 10mM in Water

Synonyms

AKOS015896389 | DTXSID30973950 | HY-113354 | L-N-beta-alanyl-3-methyl-Histidine | CHEBI:18323 | (2S)-2-[(3-ammoniopropanoyl)amino]-3-(1-methyl-1H-imidazol-5-yl)propanoate | Q415335 | (S)-2-(3-Aminopropanamido)-3-(1-methyl-1H-imidazol-5-yl)propanoicacid |

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Anserine is Carnosine's form of methylation, an orally effective, natural, histamine-containing peptide found in the skeletal muscles of vertebrates. Anserine is not lysed by serum carnosine enzymes and can be used as biochemical buffers, chelating agents, antioxidants and anti-glycation agents. Anserine improves memory function in mice with Alzheimer's disease (AD) models.

Specifications

同義語

AKOS015896389 | DTXSID30973950 | HY-113354 | L-N-beta-alanyl-3-methyl-Histidine | CHEBI:18323 | (2S)-2-[(3-ammoniopropanoyl)amino]-3-(1-methyl-1H-imidazol-5-yl)propanoate | Q415335 | (S)-2-(3-Aminopropanamido)-3-(1-methyl-1H-imidazol-5-yl)propanoicacid |

仕様と純度

10mM in Water

生化学的・生理学的メカニズム

CP-94253 is a potent and selective serotonin 5-HT1B receptor agonist with approximately 25x and 40x selectivity over the closely related 5-HT1D and 5-HT1A receptors. Ki values are 89, 2, 860, 49 and 1,600 nM for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D and 5-HT2 re

保管条件

Protected from light,Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

名前と識別子

パブケム・シド

528765258

カノニカル・スマイル

CN1C=NC=C1CC(C(=O)O)NC(=O)CCN

IUPAC Name

(2S)-2-(3-aminopropanoylamino)-3-(3-methylimidazol-4-yl)propanoic acid

InChIKey

MYYIAHXIVFADCU-QMMMGPOBSA-N

INCHI

1S/C10H16N4O3/c1-14-6-12-5-7(14)4-8(10(16)17)13-9(15)2-3-11/h5-6,8H,2-4,11H2,1H3,(H,13,15)(H,16,17)/t8-/m0/s1

異性体SMILES

CN1C=NC=C1C[C@@H](C(=O)O)NC(=O)CCN

分子量

240.26

Reaxy-Rn

89931

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=89931&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • 分類 Peptidomimetics
      • Subclass Hybrid peptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• 分類: Peptidomimetics
• Subclass: Hybrid peptides
• Intermediate Tree Nodes: Not available
• Direct Parent: Hybrid peptides
• Alternative Parents: Histidine and derivatives N-acyl-alpha amino acids Imidazolyl carboxylic acids and derivatives N-substituted imidazoles Heteroaromatic compounds Amino acids Monocarboxylic acids and derivatives Propargyl-type 1,3-dipolar organic compounds Carboxylic acids Carboximidic acids Azacyclic compounds Organic oxides Monoalkylamines Organopnictogen compounds Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Hybrid peptide - Histidine or derivatives - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Alpha-amino acid or derivatives - Imidazolyl carboxylic acid derivative - N-substituted imidazole - Azole - Imidazole - Heteroaromatic compound - Amino acid or derivatives - Amino acid - Carboximidic acid - Carboximidic acid derivative - Carboxylic acid derivative - Carboxylic acid - Azacycle - Monocarboxylic acid or derivatives - Organoheterocyclic compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Primary aliphatic amine - Carbonyl group - Organic nitrogen compound - Amine - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Primary amine - Aromatic heteromonocyclic compound
• 説明: This compound belongs to the class of organic compounds known as hybrid peptides. These are compounds containing at least two different types of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond.
• External Descriptors: beta-alanine derivative - dipeptide

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

作用メカニズム

化学的性質と物理的性質

• 比旋光度［α］: +9.0 to +13.0 deg(C=1, water)
• 融点（°C）: 238 °C
• 分子量: 240.260 g/mol
• XLogP3: -4.000
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 240.122 Da
• Monoisotopic Mass: 240.122 Da
• Topological Polar Surface Area: 110.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 285.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1