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Lincomycin - Moligand™, ≥98% , Bacterial 70S ribosome inhibitor, CAS No.154-21-2, Bacterial 70S ribosome inhibitor

CAS: 154-21-2 Cat. No.: L329314 分子式: C18H34N2O6S 分子量: 406.54 Beilstein Registry Number: 707677 EC番号: 205-824-6
32 Citations COA
Lincomycin - Moligand™, ≥98% CAS No(154-21-2) by Aladdin Scientific
注文可能
グレード＆純度 Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside
Storage
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
★
サイズ
USA
ドイツ (EU)*
価格
個数
5mg
L329314-5mg
1 在庫あり
—
$118.90
25mg
L329314-25mg
1 在庫あり
—

$342.90

$406.90
保存 $64.00 (15.73%)
100mg
L329314-100mg
1 在庫あり
—

$942.90

$1,463.90
保存 $521.00 (35.59%)
Enter a quantity for the sizes you want to add.
バルク / カスタム
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SDS
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COA
Certificate
DS
データシート
SP
仕様書
概要 仕様 製品の性質 名前と識別子 ドキュメント 詳細データ Taxonomic Classification 3 D構造 関連ターゲット（人間） 関連ターゲット（非人間） 作用メカニズム 証明書（CoA、COO、BSE/TSEと分析図） 化学的性質と物理的性質 よくある質問と記事 Citations of This Product ソリューション計算機 レビュー
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このグレードを選ぶ理由

Moligand™, ≥98% Moligand™ ベースライン干渉を最小限に抑える必要がある、感度の高いクロマトグラフィーおよび分析ワークフロー向け。

🌡

保管・配送

Store at -20°C,Argon charged Ice chest + Ice pads に出荷。正確な仕様については、ロット固有の COA をご確認ください。

📋

品質書類

SDS、COA、データシート、仕様書をダウンロードできます。ロット固有の COA はロット番号検索で入手可能です。

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文献的裏付け

クロマトグラフィー、有機合成、クロスカップリング反応に関する 32 件の査読済み論文で引用されています。

概要

Lincomycin is a polar, water soluble, broad spectrum antibiotic first isolated from|Streptomyces licolnensis|by researchers at Upjohn in 1962. Lincomycin was the first of a unique structural class, the lincosamides, containing a rare amino acid, 4-propyl-N- methylproline, coupled to an equally rare aminomethylthio- octopyranoside sugar. Lincomycin and semi-synthetic analogues are often incorrectly considered to be aminoglycosides but share little or no structural similarity. Lincomycin is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Lincomycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis. Lincomycin has been extensively studied with over 7,000 literature citations.

仕様

同義語
methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside
仕様と純度
Moligand™, ≥98%
ソース
Streptomycessp.
保管条件
Store at -20°C,Argon charged
入荷
Ice chest + Ice pads
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
等級
Moligand™
アクションタイプ
INHIBITOR
作用メカニズム
Bacterial 70S ribosome inhibitor
純度
≥98%
製品の性質
pKa
pKₐ: 12.91 (Predicted), pKₐ: 8.78 (Predicted)
ALogP
0.2
名前と識別子
パブケム・シド
528772150
カノニカル・スマイル
CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O
IUPAC Name
(2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide
InChIKey
OJMMVQQUTAEWLP-KIDUDLJLSA-N
INCHI
1S/C18H34N2O6S/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25)/t9-,10-,11+,12-,13+,14-,15-,16-,18-/m1/s1
異性体SMILES
CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@@H](C)O
RTECS
RH6314000
代替CAS番号
7179-49-9
分子量
406.54
Beilstein
707677
Reaxy-Rn
24730829
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24730829&ln=

ドキュメント

📋 安全データシート（SDS）

危険性、取扱い、保管、および規制遵守を網羅した包括的な文書。

<<<<<<< HEAD SDS をダウンロード → ======= SDS をダウンロード → >>>>>>> release248-p3

✅ 分析証明書（COA）

ロット固有の品質データ。ロット番号を入力して、正確な COA を取得してください。

COA を検索 →

📊 データシート

製品仕様と用途のクイックリファレンス概要。

データシートを見る →

🔬 仕様書

このグレードの完全な品質特性と合格基準。

仕様書を見る →

詳細データ

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
分類Carboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives
Direct ParentProline and derivatives
Alternative Parents Alpha amino acid amides  Thioglycosides  Pyrrolidinecarboxamides  Monosaccharides  N-alkylpyrrolidines  Oxanes  Monothioacetals  Trialkylamines  Secondary carboxylic acid amides  Secondary alcohols  Azacyclic compounds  Sulfenyl compounds  Oxacyclic compounds  Polyols  Organic oxides  Carbonyl compounds  Hydrocarbon derivatives  Organopnictogen compounds  
Molecular FrameworkAliphatic heteromonocyclic compounds
Substituents Proline or derivatives - Alpha-amino acid amide - Glycosyl compound - S-glycosyl compound - Pyrrolidine carboxylic acid or derivatives - Pyrrolidine-2-carboxamide - Monosaccharide - Oxane - N-alkylpyrrolidine - Monothioacetal - Pyrrolidine - Tertiary aliphatic amine - Tertiary amine - Secondary carboxylic acid amide - Secondary alcohol - Carboxamide group - Azacycle - Organoheterocyclic compound - Oxacycle - Sulfenyl compound - Polyol - Hydrocarbon derivative - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Alcohol - Organopnictogen compound - Organic oxygen compound - Organic oxide - Carbonyl group - Amine - Organic nitrogen compound - Aliphatic heteromonocyclic compound
説明This compound belongs to the class of organic compounds known as proline and derivatives. These are compounds containing proline or a derivative thereof resulting from reaction of proline at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
External Descriptors monocarboxylic acid amide - pyrrolidinecarboxamide - L-proline derivative - carbohydrate-containing antibiotic - S-glycosyl compound
3 D構造
インタラクティブ化学構造モデル





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作用メカニズム
証明書（CoA、COO、BSE/TSEと分析図）
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

13 results found

Lot NumberCertificate Type日付商品
I2628501I2628501Certificate of AnalysisOct 08, 2026 L329314
I2628502I2628502Certificate of AnalysisOct 08, 2026 L329314
I2628529I2628529Certificate of AnalysisOct 08, 2026 L329314
A2628128A2628128Certificate of AnalysisMar 11, 2024 L329314
A2628190A2628190Certificate of AnalysisMar 11, 2024 L329314
H2414134H2414134Certificate of AnalysisMar 11, 2024 L329314
H2414135H2414135Certificate of AnalysisMar 11, 2024 L329314
H2414136H2414136Certificate of AnalysisMar 11, 2024 L329314
H2414137H2414137Certificate of AnalysisMar 11, 2024 L329314
H2414138H2414138Certificate of AnalysisMar 11, 2024 L329314
H2414139H2414139Certificate of AnalysisMar 11, 2024 L329314
H2514126H2514126Certificate of AnalysisMar 11, 2024 L329314
H2612043H2612043Certificate of AnalysisMar 11, 2024 L329314
化学的性質と物理的性質
溶解度Soluble in ethanol, methanol, DMF, DMSO, and water.
感度Moisture sensitive
屈折率n20D1.58 (Predicted)
沸点（°C）~646.8° C at 760 mmHg (Predicted)
融点（°C）262.24° C (Predicted)
分子量406.500 g/mol
XLogP30.200
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Exact Mass406.214 Da
Monoisotopic Mass406.214 Da
Topological Polar Surface Area148.000 Ų
Heavy Atom Count27
Formal Charge0
Complexity498.000
Isotope Atom Count0
Defined Atom Stereocenter Count9
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
よくある質問と記事
Antibiotics block bacterial protein synthesis
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
Tags:
Antibiotics Tetra Aminoglycosides Macrolides Peptidyl transferase inhibitors Antibiotics for cell culture
How Antibiotics Halt Bacterial Protein Synthesis (With Representative Products and a Selection Guide)
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
Tags:
Antibiotics
Citations of This Product
How to Cite Aladdin Scientific Products? Citations Search
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