LM 10 - Moligand™, ≥98%(HPLC) , Inhibitor of tryptophan 2;3-dioxygenase, CAS No.1316695-35-8, Inhibitor of tryptophan 2;3-dioxygenase

Name: LM 10 - Moligand™, ≥98%(HPLC) , Inhibitor of tryptophan 2;3-dioxygenase, CAS No.1316695-35-8, Inhibitor of tryptophan 2;3-dioxygenase
SKU: L288335
Availability: InStock

CAS: 1316695-35-8 Cat. No.: L288335 分子式: C₁₁H₈FN₅ 分子量: 229.21 PubChem CID: 135743630

COA

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LM 10 - Moligand™, ≥98%(HPLC) CAS No(1316695-35-8) by Aladdin Scientific

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注文可能

GRADE & PURITY Moligand™ ? ≥98%(HPLC)

Synonyms

6-Fluoro-3-[(1E)-2-(2H-tetrazol-5-yl)ethenyl]-1H-indole

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications 名前と識別子 Documentation Advanced Data Taxonomic Classification 3 D構造関連ターゲット（人間）関連ターゲット（非人間）作用メカニズム証明書（CoA、COO、BSE/TSEと分析図）化学的性質と物理的性質ソリューション計算機レビューよくある質問

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Why this grade

Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

同義語

6-Fluoro-3-[(1E)-2-(2H-tetrazol-5-yl)ethenyl]-1H-indole

仕様と純度

Moligand™, ≥98%(HPLC)

生化学的・生理学的メカニズム

Selective tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50values are 0.62 and 2μM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. Reduces growth of TDO-expressing P815

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

INHIBITOR

作用メカニズム

Inhibitor of tryptophan 2;3-dioxygenase

純度

≥98%(HPLC)

名前と識別子

パブケム・シド	504773437
パブケム・シド・ウル	https://pubchem.ncbi.nlm.nih.gov/substance/504773437
カノニカル・スマイル	C1=CC2=C(C=C1F)NC=C2C=CC3=NNN=N3
IUPAC Name	6-fluoro-3-[(E)-2-(2H-tetrazol-5-yl)ethenyl]-1H-indole
InChIKey	JDBSZVDIUIRSDG-DAFODLJHSA-N
INCHI	1S/C11H8FN5/c12-8-2-3-9-7(6-13-10(9)5-8)1-4-11-14-16-17-15-11/h1-6,13H,(H,14,15,16,17)/b4-1+
異性体SMILES	C1=CC2=C(C=C1F)NC=C2/C=C/C3=NNN=N3
PubChem CID	135743630
MeSH用語	6-fluoro-3-(2-(3-pyridyl)vinyl)-1H-indole;680C91;LM10;TDO inhibitor LM-10;TDO inhibitor LM10
分子量	229.21

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - 分類 Indoles and derivatives
    - Subclass Indoles

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
分類	Indoles and derivatives
Subclass	Indoles
Intermediate Tree Nodes	Not available
Direct Parent	Indoles
Alternative Parents	Substituted pyrroles Benzenoids Aryl fluorides Tetrazoles Heteroaromatic compounds Azacyclic compounds Organonitrogen compounds Organofluorides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Indole - Aryl fluoride - Aryl halide - Substituted pyrrole - Benzenoid - Azole - Heteroaromatic compound - Pyrrole - Tetrazole - Azacycle - Organofluoride - Organohalogen compound - Organic nitrogen compound - Organonitrogen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound
説明	This compound belongs to the class of organic compounds known as indoles. These are compounds containing an indole moiety, which consists of pyrrole ring fused to benzene to form 2,3-benzopyrrole.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3 D構造

Lot Number	Certificate Type	日付	商品
I2203346	Certificate of Analysis	Jun 10, 2025	L288335
I2203347	Certificate of Analysis	Jun 10, 2025	L288335
I2205061	Certificate of Analysis	Jun 10, 2025	L288335
I2205062	Certificate of Analysis	Jun 10, 2025	L288335
I2205063	Certificate of Analysis	Jun 10, 2025	L288335

溶解度	Solvent:DMSO, Max Conc. mg/mL: 22.92, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 4.58, Max Conc. mM: 20 with gentle warming
分子量	229.210 g/mol
XLogP3	2.000
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	229.076 Da
Monoisotopic Mass	229.076 Da
Topological Polar Surface Area	70.300 Å²
Heavy Atom Count	17
Formal Charge	0
Complexity	298.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1

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レビュー

よくある質問

What is the purity of this product, and how is it determined?

This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1316695-35-8, the molecular formula is C11H8FN5, and the molecular weight is 229.21 g/mol. InChIKey JDBSZVDIUIRSDG-DAFODLJHSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Moligand™ grade guide →

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