LT175 - Moligand™, 10 mM in DMSO , CAS No.862901-87-9

CAS: 862901-87-9 Cat. No.: L1495399 分子式: C₂₁H₁₈O₃ 分子量: 318.37 EC番号: 109-899-5 PubChem CID: 11483970

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

LT175, a dual PPARα/γ ligand, is an orally active partial agonist against PPARγ (hPPARα: EC 50 =0.22 μm; mPPARα: EC 50 =0.26 μm; hPPARγ: EC 50 =0.48 μm). LT175 interacts with PPARγ and affects the recruitment of the coregulators cyclic-AMP response element-binding protein-binding protein and nuclear corepressor 1 (NCoR1). LT175 interacts with PPARγ in a hydrophobic region called “diphenyl pocket”. LT175 has potent insulin-sensitizing effects and reduced adipogenic properties.

Specifications

仕様と純度

Moligand™, 10 mM in DMSO

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

AGONIST

名前と識別子

異性体SMILES

C1=CC=C(C=C1)C[C@@H](C(=O)O)OC2=CC=C(C=C2)C3=CC=CC=C3

PubChem CID

11483970

分子量

318.37