Name: Luteolin - Moligand™, 10mM in DMSO , Agonist of TAS2R14;Agonist of TAS2R39, CAS No.491-70-3, Agonist of TAS2R14;Agonist of TAS2R39
SKU: L409168
Availability: InStock

Luteolin - Moligand™, 10mM in DMSO , Agonist of TAS2R14;Agonist of TAS2R39, CAS No.491-70-3, Agonist of TAS2R14;Agonist of TAS2R39

CAS: 491-70-3 Cat. No.: L409168 分子式: C₁₅H₁₀O₆ 分子量: 286.24 Beilstein Registry Number: 292084 EC番号: 207-741-0

概要 Specifications 名前と識別子 Documentation Advanced Data 関連ターゲット（人間）証明書（CoA、COO、BSE/TSEと分析図）化学的性質と物理的性質よくある質問と記事 Citations of This Product ソリューション計算機レビュー

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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 223 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

概要

Information

Luteolin (Luteoline, Luteolol, Digitoflavone) is a flavonoid found in Terminalia chebula, which is a non-selective phisphodiesterase PDE inhibitor for PDE1-5 with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM, respectively. Phase 2.
In vitro

Luteolin is a flavonoid found in Terminalia chebula, which is a non-selective phisphodiesterase PDE inhibitor for PDE1-5 with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM, respectively. Luteolin inhibits LPS-stimulated TNF-alpha production with an IC50 of less than 1 μM. Luteolin inhibites LPS-induced phosphorylation of Akt as well as IkappaBalpha.

In vivo

LD50: Mice >2500mg/kg (i.g.)
Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥97%

Specifications

同義語

Luteoline, Luteolol, Digitoflavone | 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-

仕様と純度

Moligand™, 10mM in DMSO

生化学的・生理学的メカニズム

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

AGONIST

作用メカニズム

Agonist of TAS2R14;Agonist of TAS2R39

名前と識別子

異性体SMILES

C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O

WGKドイツ

RTECS

LK9275210

分子量

286.24

Beilstein

292084

Reaxy-Rn

292084

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=292084&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

関連ターゲット（人間）

CYP1A2 Tchem Cytochrome P450 1A2 (1 Activities)

Discover Target: CYP1A2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP1B1 Tchem Cytochrome P450 1B1 (3 Activities)

Discover Target: CYP1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DPP4 Tclin Dipeptidyl peptidase 4 (1 Activities)

Discover Target: DPP4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TTR Tclin Transthyretin (1 Activities)

Discover Target: TTR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MMP12 Tchem Macrophage metalloelastase (1 Activities)

Discover Target: MMP12

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CA4 Tclin Carbonic anhydrase 4 (1 Activities)

Discover Target: CA4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CA12 Tclin Carbonic anhydrase 12 (1 Activities)

Discover Target: CA12

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CA7 Tclin Carbonic anhydrase 7 (1 Activities)

Discover Target: CA7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP1A1 Tchem Cytochrome P450 1A1 (1 Activities)

Discover Target: CYP1A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

XDH Tclin Xanthine dehydrogenase/oxidase (1 Activities)

Discover Target: XDH

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AKR1B1 Tclin Aldose reductase (1 Activities)

Discover Target: AKR1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NOX4 Tchem NADPH oxidase 4 (1 Activities)

Discover Target: NOX4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

証明書（CoA、COO、BSE/TSEと分析図）

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number	Certificate Type	日付	商品
I2624544	Certificate of Analysis	Oct 10, 2026	L409168
L2201020	Certificate of Analysis	Aug 11, 2026	L409168

化学的性質と物理的性質

溶解度	Solubility (25°C) In vitro DMSO: 38 mg/mL (102.73 mM); Water: 10 mg/mL (27.03 mM); Ethanol: 2 mg/mL (5.4 mM);
融点（°C）	330°C

よくある質問と記事

Molecular Basis of Glycosylation Modification and Functional Release in Natural Products

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Natural products glycosylation modification glycosyltransferases glycosidases precursor activation functional release deglycosylation structure-activity relationship

Extraction Methods and Process Selection for Flavonoid Compounds

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

flavonoid compounds extraction methods solvent extraction ultrasound-assisted extraction microwave-assisted extraction enzyme-assisted extraction supercritical fluid extraction process optimization

Mechanisms by Which Flavonoid Natural Products Regulate the Oxidative Stress-Inflammation Axis

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Inflammation Natural products Oxidative Stress Reactive oxygen species Nrf2 NLRP3 flavonoids NF-kappaB

Scientific Rationale and Application Assessment of Olive Leaf Extract in Skin Redness Care

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

vasodilation Sensory nerve activation

Mechanisms of Action, Representative Compounds, and Research Applications of Senolytics

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Senolytics SASP SCAP Navitoclax cellular senescence senescence-associated secretory phenotype dasatinib quercetin fisetin

Antidiabetic Mechanisms, Representative Bioactive Compounds, and Research Applications of Natural Products

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Natural products diabetes mellitus Oxidative Stress Insulin Resistance gut microbiota drug screening Pancreatic β cells Hepatic Gluconeogenesis Glucose Uptake

Regulatory Mechanisms of Aging-Related Nutrient Sensing, Inflammation, and Homeostatic Signaling Pathways

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Autophagy Aging mTOR AMPK senescence-associated secretory phenotype IIS IGF-1 Sirtuins

Molecular Mechanisms by Which Natural Products Regulate Adipose Browning

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Natural products AMPK adipose browning white adipose tissue UCP1 PGC-1α Hyperforin non-shivering thermogenesis

Glycosidic Bond Structure and Cleavage Mechanisms—Chemical and Enzymatic Cleavage of O-, N-, S-, and C-Glycosides

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

O-glycosides C-glycosides Glycosides

Citations of This Product

How to Cite Aladdin Scientific Products? Citations Search

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レビュー

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Luteolin - Moligand™, 10mM in DMSO , Agonist of TAS2R14;Agonist of TAS2R39, CAS No.491-70-3, Agonist of TAS2R14;Agonist of TAS2R39

Storage & shipping

Quality documents

Literature proof

概要

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

顧客レビュー

📚 Citations by Application

Need help choosing the grade?

Luteolin - Moligand™, 10mM in DMSO , Agonist of TAS2R14;Agonist of TAS2R39, CAS No.491-70-3, Agonist of TAS2R14;Agonist of TAS2R39

Storage & shipping

Quality documents

Literature proof

概要

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

顧客レビュー

📚 Citations by Application

Need help choosing the grade?

View related series