m-PEG-NHS ester - MW5000 , CAS No.92451-01-9

CAS: 92451-01-9 Cat. No.: M658882 分子式: (C₂H₄O)nC₇H₉NO₅ 分子量: 293.27 PubChem CID: 71312614

GRADE & PURITY MW5000

Synonyms

Methoxypolyethylene glycol 5,000 acetic acid N-succinimidyl ester | mono-Methyl polyethylene glycol 5′000 acetic acid N-succinimidyl ester | Succinimidyl ester of carboxymethyl-PEG | mPEG-SC (MW 5000) | mPEG-Succinimidyl ester (MW 5000)

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

概要

The m-PEG-NHS ester (MW 5000) is a PROTAC linker belonging to the PEG class. It can be used to synthesize PROTAC molecules

m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Appearance:Solid

IC50& Target:PEGs Alkyl/ether

In Vitro:PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. MCE

Biological Activity:m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Specifications

同義語

Methoxypolyethylene glycol 5,000 acetic acid N-succinimidyl ester | mono-Methyl polyethylene glycol 5′000 acetic acid N-succinimidyl ester | Succinimidyl ester of carboxymethyl-PEG | mPEG-SC (MW 5000) | mPEG-Succinimidyl ester (MW 5000)

仕様と純度

MW5000

保管条件

Protected from light,Store at -20°C,Argon charged

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

名前と識別子

カノニカル・スマイル

COCCO.C1CC(=O)N(C1=O)OC(=O)COCCO

IUPAC Name

(2,5-dioxopyrrolidin-1-yl) 2-(2-hydroxyethoxy)acetate;2-methoxyethanol

InChIKey

NYXRHTOXAYVBMV-UHFFFAOYSA-N

INCHI

1S/C8H11NO6.C3H8O2/c10-3-4-14-5-8(13)15-9-6(11)1-2-7(9)12;1-5-3-2-4/h10H,1-5H2;4H,2-3H2,1H3

異性体SMILES

COCCO.C1CC(=O)N(C1=O)OC(=O)COCCO

WGKドイツ

3

PubChem CID

71312614

分子量

293.27

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 分類 Pyrrolidines
      • Subclass Pyrrolidones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 分類: Pyrrolidines
• Subclass: Pyrrolidones
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyrrolidine-2-ones
• Alternative Parents: Dicarboximides Lactams Monocarboxylic acids and derivatives Dialkyl ethers Azacyclic compounds Primary alcohols Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Not available
• Substituents: 2-pyrrolidone - Dicarboximide - Lactam - Carboxylic acid derivative - Dialkyl ether - Ether - Monocarboxylic acid or derivatives - Azacycle - Organonitrogen compound - Alcohol - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Organooxygen compound - Primary alcohol - Organic oxide - Hydrocarbon derivative - Aliphatic heteromonocyclic compound
• 説明: This compound belongs to the class of organic compounds known as pyrrolidine-2-ones. These are pyrrolidines which bear a C=O group at position 2 of the pyrrolidine ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

化学的性質と物理的性質

• 感度: Light Sensitive；Moisture Sensitive

よくある質問

How should this product be stored?

Store at ?20 °C, protected from light, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 92451-01-9, the molecular formula is (C2H4O)nC7H9NO5, and the molecular weight is 293.27 g/mol. InChIKey NYXRHTOXAYVBMV-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.