グレード＆純度Analytical standard?Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.≥98%
Matrine (MT) or Sophocarpidine is a naturally occurring bioactive compound, extracted from traditional Chinese herbs like Sophora flavescens and Radix Sophorae tonkinensis.
Application
Matrine has been used:
to study its antioxidant and protective effect on doxorubicin (DOX)-induced cardiotoxicity in mice model and H9C2 cells.
as a chemotherapeutic agent to test its inhibitory effect on the growth of human glioblastoma multiforme (GBM) cells, and ovarian cancer cells.
to study its effect on mitochondrial fission and its anti-tumor functionality in HepG2 cells.
as a necroptosis inducer in cholangiocarcinoma (CCA) cell lines.
This compound belongs to the class of organic compounds known as matrine alkaloids. These are lupin alkaloids with a structure based on the matrine skeleton, a four-ring skeleton that based on a saturated dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one skeleton.
External Descriptors
Alkaloids - Quinolizidine alkaloids
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
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H2505404