10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Memantine HCl Memantine HCl is an antagonist of NMDAR . It is also a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6 with IC50 of 1.12 μM and 242.4 μM, Ki of 0.51 μM and 84.4 μM, respectively.
In vitro
In vivo
Cell Data
cell lines：
Concentrations：
Incubation Time：
Powder Purity:≥100%
| 異性体SMILES | CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl |
|---|---|
| WGKドイツ | 3 |
| 分子量 | 215.76 |
| Reaxy-Rn | 6573843 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6573843&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| 融点（°C） | 292°C |
|---|
| 1. Jiawen Han, Yaru Ding, Xujuan Lv, Yuwei Zhang, Daoqing Fan. (2023) Integration of G-Quadruplex and Pyrene as a Simple and Efficient Ratiometric Fluorescent Platform That Programmed by Contrary Logic Pair for Highly Sensitive and Selective Coralyne (COR) Detection. Biosensors-Basel, 13 (4): (489). [PMID:37185564] [10.3390/bios13040489] |
| 2. Fangfang Shen, Dingqiang Lu, Xiuquan Ling, Xinxian Wang, Tongqi Liu, Tianhua Huang, Kefei He. (2016) Thermodynamic analysis and calculation of solubility of Memantine hydrochloride in ethanol plus (acetonitrile, water, ethyl acetate) binary solvent mixtures. JOURNAL OF MOLECULAR LIQUIDS, [PMID:] [10.1016/j.molliq.2016.12.051] |
| 3. Gong Chen, Panyang Gu, Wenfang Wu, Yuan Yin, Liangyu Pan, Shu Huang, Wei Lin, Meichun Deng. (2024) SETD2 deficiency in peripheral sensory neurons induces allodynia by promoting NMDA receptor expression through NFAT5 in rodent models. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:39476923] [10.1016/j.ijbiomac.2024.136767] |
