Methylthiouracil - 10mM in DMSO , CAS No.56-04-2

CAS: 56-04-2 Cat. No.: M408545 分子式: C₅H₆N₂OS 分子量: 142.18 EC番号: 200-252-3

グレード＆純度 10mM in DMSO

Synonyms

NSC-193526, NSC-9378 | 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Information

Methylthiouracil (NSC-193526, NSC-9378) is an antithyroid agent. Methylthiouracil suppresses the productionTNF-αandIL-6, and the activation ofNF-κBandERK1/2.
In vitro

Methylthiouracil acts to decrease the formation of stored thyroid hormone, as thyroglobulin in the thyroid gland. Methylthiouracil is also used in combination with radioactive iodine.

In vivo

Cell Data

cell lines：MM1.S, MM.1R, LR5, RPMI 8226, DOX40, OPM1, OPM2, INA6, and U266

Concentrations：

Incubation Time：

Powder Purity:≥99%

仕様

同義語

NSC-193526, NSC-9378 | 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

仕様と純度

10mM in DMSO

生化学的・生理学的メカニズム

Methylthiouracil (NSC-193526, NSC-9378) is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

名前と識別子

異性体SMILES

CC1=CC(=O)NC(=S)N1

UN番号

3077

包装グループ

III

分子量

142.18

Reaxy-Rn

115648

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=115648&ln=

化学的性質と物理的性質

• 溶解度: Solubility (25°C) In vitro DMSO: 64 mg/mL (199.17 mM); Water: Insoluble; Ethanol: Insoluble
• 融点（°C）: 330°C